Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | TEK | Q02763 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.48 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 2/20 | 0.46 |
| ▸ | BRAF | P15056 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18004132 | 0.85 | MAPT (0.58) | MAPTALDH1A1CSNK1DDYRK1APPARA | |
| SCHEMBL16398809 | 0.85 | ALDH1A1 (0.63) | MAPTALDH1A1HSD17B1HSD17B2MAOA | |
| SCHEMBL21945012 | 0.85 | ALDH1A1 (0.56) | MAPTALDH1A1DYRK1AKCNH2HSD17B1 | |
| SCHEMBL21945149 | 0.84 | ALDH1A1 (0.55) | MAPTALDH1A1CSNK1DDYRK1AHSD17B1 | |
| SCHEMBL7158014 | 0.81 | MAPT (0.64) | MAPTALDH1A1CSNK1DDYRK1AHSD17B1 | |
| SCHEMBL17161588 | 0.80 | DYRK1A (0.60) | MAPTALDH1A1CSNK1DDYRK1APPARA | |
| SCHEMBL21945689 | 0.78 | MAPT (0.47) | MAPTKDRTEKCSNK1DCACNA1B | |
| SCHEMBL18004108 | 0.76 | SCN4A (0.70) | MAPTALDH1A1CACNA1BKCNH2 | |
| SCHEMBL30451659 | 0.76 | SCN4A (0.70) | MAPTALDH1A1CACNA1BKCNH2 | |
| SCHEMBL25219141 | 0.75 | MAPT (0.64) | MAPTALDH1A1CSNK1DDYRK1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | MAPT 2196/4885KDR 2214/4885TEK 1660/4885 |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | CS, PC, ACAT1 | MAPT 2196/4885KDR 2214/4885TEK 1660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.