Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1124429 | 1.00 | MEN1 (0.42) | MEN1KMT2AHSD17B10ALDH1A1PTGS2 | |
| Hydrochloric Acid SCHEMBL20502547 | 0.98 | ALDH1A1 (0.42) | MEN1KMT2AHSD17B10ALDH1A1PTGS2 | |
| Hydrochloric Acid SCHEMBL31752348 | 0.98 | ALDH1A1 (0.42) | MEN1KMT2AHSD17B10ALDH1A1PTGS2 | |
| Hydrochloric Acid SCHEMBL31753224 | 0.89 | ALDH1A1 (0.40) | MEN1KMT2AHSD17B10ALDH1A1PTGS2 | |
| SCHEMBL3898092 | 0.87 | ALDH1A1 (0.39) | MEN1KMT2AHSD17B10ALDH1A1ACACB | |
| SCHEMBL3898104 | 0.87 | ALDH1A1 (0.39) | MEN1KMT2AHSD17B10ALDH1A1ACACB | |
| SCHEMBL3628791 | 0.84 | MKNK1 (0.45) | ALDH1A1PTGS2ACACBAAK1 | |
| SCHEMBL14713190 | 0.84 | MKNK1 (0.45) | ALDH1A1PTGS2ACACBAAK1 | |
| SCHEMBL25353489 | 0.83 | GRIA1 (0.49) | HSD17B10PTGS2 | |
| SCHEMBL21946640 | 0.83 | GRIA1 (0.49) | HSD17B10PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11345669-B2 | Urea derivatives and methods of use thereof | NodThera Limited (GB) | 2022-05-31 | — | — | US | disclosed |
| US-20200131141-A1 | CHEMICAL COMPOUNDS | NodThera Limited (GB) | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131141-A1 | CHEMICAL COMPOUNDS | IL1B, CASP1, IL1A | MEN1 888/4885KMT2A 4501/4885HSD17B10 1789/4885 |
| US-11345669-B2 | Urea derivatives and methods of use thereof | IL1B, IL1A, NOD1 | MEN1 1001/4885KMT2A 4408/4885HSD17B10 2652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.