SCHEMBL2194689

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9610373	0.92	TAS1R3 (0.36)	PIN1TAS1R3TAS1R1ALDH1A1MEN1
	SCHEMBL9610389	0.91	ALDH1A1 (0.36)	PIN1LMNATAS1R3TAS1R1ALDH1A1
	SCHEMBL9610377	0.86	PIN1 (0.36)	PIN1LMNATAS1R3TAS1R1MEN1
	SCHEMBL2192132	0.86	CYP2D6 (0.35)	ALDH1A1HPGDPOLB
	SCHEMBL2819925	0.86	POLB (0.46)	PIN1CCR6LMNAALDH1A1HPGD
	SCHEMBL9610374	0.84	PIN1 (0.34)	PIN1LMNATAS1R3TAS1R1ALDH1A1
	SCHEMBL9610376	0.84	LMNA (0.36)	PIN1LMNATAS1R3TAS1R1ALDH1A1
	SCHEMBL9610372	0.83	KMT2A (0.37)	PIN1LMNATAS1R3TAS1R1ALDH1A1
	SCHEMBL9610369	0.82	KMT2A (0.36)	PIN1LMNATAS1R3TAS1R1ALDH1A1
	SCHEMBL9610371	0.82	TAS1R3 (0.36)	PIN1LMNATAS1R3TAS1R1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.