Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337155 | 1.00 | FDPS (0.48) | FDPSKMT2APKMNAPRTTBXAS1 | |
| SCHEMBL20543866 | 1.00 | FDPS (0.48) | FDPSKMT2APKMNAPRTTBXAS1 | |
| Hydrochloric Acid SCHEMBL29657240 | 0.99 | FDPS (0.47) | FDPSKMT2APKMNAPRTTBXAS1 | |
| Hydrochloric Acid SCHEMBL29115300 | 0.99 | FDPS (0.47) | FDPSKMT2APKMNAPRTTBXAS1 | |
| Hydrochloric Acid SCHEMBL29115298 | 0.99 | FDPS (0.47) | FDPSKMT2APKMNAPRTTBXAS1 | |
| Hydrochloric Acid SCHEMBL6980665 | 0.99 | FDPS (0.47) | FDPSKMT2APKMNAPRTTBXAS1 | |
| SCHEMBL19699200 | 0.87 | ALDH1A1 (0.49) | FDPSKMT2APKMNAPRTTBXAS1 | |
| SCHEMBL2058766 | 0.87 | ALDH1A1 (0.49) | FDPSKMT2APKMNAPRTTBXAS1 | |
| SCHEMBL29627252 | 0.87 | ALDH1A1 (0.49) | FDPSKMT2APKMNAPRTTBXAS1 | |
| SCHEMBL1693107 | 0.87 | ALDH1A1 (0.49) | FDPSKMT2APKMNAPRTTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11345669-B2 | Urea derivatives and methods of use thereof | NodThera Limited (GB) | 2022-05-31 | — | — | US | disclosed |
| US-20200131141-A1 | CHEMICAL COMPOUNDS | NodThera Limited (GB) | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131141-A1 | CHEMICAL COMPOUNDS | IL1B, CASP1, IL1A | FDPS 232/4885KMT2A 4501/4885PKM 3140/4885 |
| US-11345669-B2 | Urea derivatives and methods of use thereof | IL1B, IL1A, NOD1 | FDPS 578/4885KMT2A 4408/4885PKM 2439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.