Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31248369 | 0.85 | ALDH1A1 (0.54) | ADRB2ADRB1ADRB3CYP26A1L3MBTL1 | |
| SCHEMBL29788361 | 0.84 | CYP26A1 (0.49) | CYP26A1L3MBTL1KDM4EMAPTALDH1A1 | |
| SCHEMBL7948541 | 0.81 | CYP26A1 (0.47) | CYP26A1L3MBTL1KDM4EMAPTALDH1A1 | |
| SCHEMBL7905129 | 0.76 | LNPEP (0.57) | L3MBTL1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL6093237 | 0.75 | GAA (0.64) | CYP26A1ALDH1A1CYP2C19 | |
| SCHEMBL27822263 | 0.75 | ALDH1A1 (0.53) | L3MBTL1KDM4EALDH1A1MPOCYP1A2 | |
| SCHEMBL11640564 | 0.75 | ADRB2 (0.59) | ADRB2ADRB1ADRB3L3MBTL1KDM4E | |
| SCHEMBL14755265 | 0.74 | CYP26A1 (0.55) | CYP26A1L3MBTL1TAS1R3TAS1R1CYP3A4 | |
| Hydrochloric Acid SCHEMBL8133315 | 0.74 | GAA (0.62) | CYP26A1ALDH1A1CYP2C19 | |
| SCHEMBL23303748 | 0.73 | TAS1R3 (0.60) | L3MBTL1ALDH1A1TAS1R3TAS1R1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11136295-B2 | D-amphetamine compounds, compositions, and processes for making and using the same | KEMPHARM, INC. (US) | 2021-10-05 | — | — | US | disclosed |
| US-20200131130-A1 | D-AMPHETAMINE COMPOUNDS, COMPOSITIONS, AND PROCESSES FOR MAKING AND USING THE SAME | ALTER DOMUS (US) LLC | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131130-A1 | D-AMPHETAMINE COMPOUNDS, COMPOSITIONS, AND PROCESSES FOR MAKING AND USING THE SAME | DDT, COMT, DDC | ADRB2 728/4885ADRB1 450/4885ADRB3 391/4885 |
| US-11136295-B2 | D-amphetamine compounds, compositions, and processes for making and using the same | DDT, COMT, DDC | ADRB2 728/4885ADRB1 450/4885ADRB3 391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.