Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MGLL | Q99685 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | LPL | P06858 | 2/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789866 | 0.81 | ENPP2 (0.70) | ENPP2KDM4EALDH1A1MGLLCA4 | |
| SCHEMBL3275789 | 0.79 | TRPV6 (0.61) | ENPP2KDM4EALDH1A1MGLLCA4 | |
| SCHEMBL30712840 | 0.74 | MGLL (0.86) | ENPP2KDM4EALDH1A1MGLLCA4 | |
| SCHEMBL31139484 | 0.74 | MGLL (0.86) | ENPP2KDM4EALDH1A1MGLLCA4 | |
| SCHEMBL12619984 | 0.74 | MGLL (0.86) | ENPP2KDM4EALDH1A1MGLLCA4 | |
| Ethylene SCHEMBL4455146 | 0.73 | ENPP2 (0.54) | ENPP2KDM4EALDH1A1MGLLCA4 | |
| SCHEMBL3274723 | 0.72 | TRPV6 (0.35) | ENPP2MGLL | |
| SCHEMBL4933 | 0.72 | ENPP2 (0.58) | ENPP2KDM4EALDH1A1MGLLCA4 | |
| SCHEMBL8884 | 0.72 | ENPP2 (1.00) | ENPP2KDM4EALDH1A1MGLLCA4 | |
| SCHEMBL29547555 | 0.72 | ENPP2 (0.58) | ENPP2KDM4EALDH1A1MGLLCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751577-B1 | A method of manufacturing a sterilized optical analyte sensor | MEDTRONIC MINIMED INC (US) | 2019-04-17 | — | — | EP | disclosed |
| EP-2989975-B1 | OPTICAL SYSTEMS AND METHODS FOR RATIONMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION | MEDTRONIC MINIMED INC (US) | 2018-06-13 | — | — | EP | disclosed |
| US-9839378-B2 | Optical systems and methods for ratiometric measurement of blood glucose concentration | MEDTRONIC MINIMED, INC. (US) | 2017-12-12 | — | — | US | disclosed |
| US-9757057-B2 | Dry insertion and one-point in vivo calibration of an optical analyte sensor | MEDTRONIC MINIMED, INC. (US) | 2017-09-12 | — | — | US | disclosed |
| US-9693720-B2 | Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement | MEDTRONIC MINIMED, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| EP-2989975-A1 | OPTICAL SYSTEMS AND METHODS FOR RATIONMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION | Medtronic MiniMed, Inc. (US) | 2016-03-02 | — | — | EP | disclosed |
| EP-2916722-A1 | DRY INSERTION AND ONE-POINT IN VIVO CALIBRATION OF AN OPTICAL ANALYTE SENSOR | Medtronic MiniMed, Inc. (US) | 2015-09-16 | — | — | EP | disclosed |
| US-20150080685-A1 | EQUILIBRIUM NON-CONSUMING FLUORESCENCE SENSOR FOR REAL TIME INTRAVASCULAR GLUCOSE MEASUREMENT | MEDTRONIC MINIMED, INC. (US) | 2015-03-19 | — | — | US | disclosed |
| US-8979790-B2 | Use of an equilibrium sensor to monitor glucose concentration | MEDTRONIC MINIMED, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-8983565-B2 | Optical determination of pH and glucose | MEDTRONIC MINIMED, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| WO-2007067743-A2 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS-II | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-06-14 | — | — | WO | disclosed |
| US-20060083688-A1 | Optical determination of glucose utilizing boronic acid adducts | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-04-20 | — | — | US | disclosed |
| US-20040028612-A1 | Optical determination of glucose utilizing boronic acid adducts | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2004-02-12 | — | — | US | disclosed |
| US-6653141-B2 | In vitro detection of polyhydroxyl-substituted organic molecules; obtain sample, incubate in fluorescent dye exposure to excitation light detect and measure signal | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-11-25 | — | — | US | disclosed |
| US-6627177-B2 | Obtaining flurorophore dye which is compatible with the analyte solution; combining withboronic acid-containing quencher molecule; contacting with excitation light source coupled with a detector; producing signal; quantification | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-09-30 | — | — | US | disclosed |
| EP-1340076-A2 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | The Regents of the University of California (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002046752-A9 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | UNIV CALIFORNIA (US) | 2002-08-29 | — | — | WO | disclosed |
| US-20020106326-A1 | Polyhydroxyl-substituted organic molecule sensing optical in vivo method utilizing a boronic acid adduct and the device thereof | CALIFORNIA, UNIVERSITY OF THE REGENTS OF THE | 2002-08-08 | — | — | US | disclosed |
| US-20020106810-A1 | Polyhydroxyl-substituted organic molecule sensing optical in vitro method utilizing a boronic acid adduct and the device thereof | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2002-08-08 | — | — | US | disclosed |
| WO-2002046752-A2 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040028612-A1 | Optical determination of glucose utilizing boronic acid adducts | NISCH, BLVRB, FOSB | ENPP2 3886/4885KDM4E 2992/4885ALDH1A1 959/4885 |
| US-20060083688-A1 | Optical determination of glucose utilizing boronic acid adducts | NISCH, FOSB, BLVRB | ENPP2 3653/4885KDM4E 2991/4885ALDH1A1 1006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.