Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221260 | 0.83 | MAOB (0.46) | MAOBNLRP3ACHEDRD2 | |
| SCHEMBL222333 | 0.78 | MAOB (0.52) | MAOBACHEDRD2 | |
| SCHEMBL222398 | 0.77 | MAOB (0.41) | MAOBNLRP3ACHEDRD2HPGD | |
| SCHEMBL4592502 | 0.76 | MAOB (0.50) | MAOBACHE | |
| SCHEMBL4592504 | 0.75 | MAOB (0.49) | MAOBACHEDRD2HPGD | |
| SCHEMBL4592501 | 0.74 | MAOB (0.48) | MAOBACHEHPGD | |
| SCHEMBL11090037 | 0.74 | — | — | |
| SCHEMBL3761385 | 0.74 | MAOB (0.50) | MAOBNLRP3ACHE | |
| SCHEMBL223192 | 0.73 | HTR2A (0.34) | HTR2AHTR2CUSP2HPGDHSD17B10 | |
| SCHEMBL3963524 | 0.68 | MAOB (1.00) | MAOBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088925-B2 | low molecular weight factor Xa specific blood clotting inhibitors; less side effects; 5-Chloro-thiophene-2-carboxylic acid [2-(1-isopropyl-piperidin-4-ylsulfamoyl)-ethyl]-amide; thromboembolic diseases or restenosis; antithrombotic agents | SANOFI-AVENTIS (FR) | 2012-01-03 | — | — | US | disclosed |