Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GALK1 | P51570 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592504 | 0.83 | MAOB (0.49) | MAOBALDH1A1KMT2AHPGDMAPT | |
| Taurine SCHEMBL4593156 | 0.76 | SMN1; SMN2 (0.42) | ALDH1A1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL496740 | 0.75 | GLS (0.53) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL222333 | 0.75 | MAOB (0.52) | MAOBALDH1A1ACHE | |
| SCHEMBL219546 | 0.74 | MAOB (0.51) | MAOBHPGDACHE | |
| Potassium SCHEMBL6284198 | 0.74 | GLS (0.52) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL6284185 | 0.74 | GLS (0.52) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL4592502 | 0.73 | MAOB (0.50) | MAOBALDH1A1PKMMAPTACHE | |
| SCHEMBL2782845 | 0.71 | SMN1; SMN2 (0.53) | ALDH1A1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL221260 | 0.69 | MAOB (0.46) | MAOBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888567-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | Sanofi-Aventis (FR) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006122661-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI-AVENTIS (DE) | 2006-11-23 | — | — | WO | disclosed |