Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592502 | 0.84 | MAOB (0.50) | MAOBACHEALDH1A1 | |
| SCHEMBL221237 | 0.83 | ACHE (0.42) | ACHEDRD2ALDH1A1KDM1A | |
| SCHEMBL4592504 | 0.83 | MAOB (0.49) | MAOBACHEDRD2ALDH1A1KDM1A | |
| SCHEMBL219755 | 0.78 | HTR1A (0.42) | MAOBACHEHTR1AALDH1A1KDM1A | |
| SCHEMBL219546 | 0.78 | MAOB (0.51) | MAOBACHEDRD2 | |
| SCHEMBL19739574 | 0.75 | HPGD (0.56) | ACHEHTR1AHTR7ALDH1A1 | |
| SCHEMBL4592501 | 0.75 | MAOB (0.48) | MAOBACHEALDH1A1 | |
| Taltrimide SCHEMBL347001 | 0.74 | NPSR1 (0.48) | MAOBALDH1A1 | |
| Taltrimide SCHEMBL29866257 | 0.74 | NPSR1 (0.48) | MAOBALDH1A1 | |
| SCHEMBL13102745 | 0.73 | F10 (0.49) | F10HTR1AHTR7DRD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088925-B2 | low molecular weight factor Xa specific blood clotting inhibitors; less side effects; 5-Chloro-thiophene-2-carboxylic acid [2-(1-isopropyl-piperidin-4-ylsulfamoyl)-ethyl]-amide; thromboembolic diseases or restenosis; antithrombotic agents | SANOFI-AVENTIS (FR) | 2012-01-03 | — | — | US | disclosed |