SCHEMBL2198773

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2196975	0.89	IKBKB (0.47)	KDM4EALDH1A1LMNAFFAR1BRD4
	SCHEMBL4345702	0.82	BRD4 (0.47)	KDM4EALDH1A1LMNAFFAR1BRD4
	SCHEMBL2200763	0.80	JAK2 (0.47)	KDM4EALDH1A1LMNABRD4JAK2
	SCHEMBL2195873	0.79	BRD4 (0.47)	KDM4EALDH1A1BRD4JAK2IKBKB
	SCHEMBL2196845	0.78	CDC7 (0.51)	FFAR1BRD4JAK2PARP1IKBKB
	SCHEMBL2198463	0.78	BRD4 (0.52)	FFAR1BRD4JAK2IKBKBBTK
	SCHEMBL2198478	0.77	BRD4 (0.46)	KDM4EALDH1A1BRD4
	SCHEMBL2196489	0.77	IKBKB (0.52)	KDM4EBRD4JAK2PARP1IKBKB
	SCHEMBL13446750	0.76	BRD4 (0.39)	BRD4JAK2PARP1IKBKBJAK3
	SCHEMBL13446706	0.76	BRD4 (0.37)	BRD4JAK2PARP1IKBKBJAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.