Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 5/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20084781 | 0.85 | CASP1 (0.40) | CASP1HTR2ASLC6A4PARP10L3MBTL1 | |
| SCHEMBL20085355 | 0.83 | ALDH1A1 (0.40) | CASP1HTR2ASLC6A4PARP10L3MBTL1 | |
| SCHEMBL5680753 | 0.78 | CASP1 (0.63) | CASP1HTR2ASLC6A4KCNH2ALDH1A1 | |
| SCHEMBL20084804 | 0.77 | HTR2A (0.55) | HTR2ASLC6A4PARP10KCNH2GCK | |
| SCHEMBL6290582 | 0.74 | SLC6A4 (0.40) | CASP1HTR2ASLC6A4L3MBTL1KCNH2 | |
| SCHEMBL6289858 | 0.74 | SLC6A4 (0.40) | CASP1HTR2ASLC6A4L3MBTL1KCNH2 | |
| SCHEMBL18928639 | 0.73 | TSHR (0.39) | CASP1TSHR | |
| SCHEMBL16792505 | 0.73 | GCK (0.48) | HTR2ASLC6A4PARP10L3MBTL1KCNH2 | |
| SCHEMBL30764801 | 0.73 | GCK (0.48) | HTR2ASLC6A4PARP10L3MBTL1KCNH2 | |
| SCHEMBL25962922 | 0.72 | HTR2A (0.49) | HTR2ASLC6A4PARP10KCNH2GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312172-B1 | AMINOPYRAZOLE DERIVATIVES USEFUL AS SRC KINASE INHIBITORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2020-05-06 | — | — | EP | disclosed |