Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.52 |
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | PPARD | Q03181 | 7/20 | 0.52 |
| ▸ | PPARA | Q07869 | 7/20 | 0.52 |
| ▸ | TSHR | P16473 | 6/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutarate SCHEMBL5875071 | 1.00 | SLC22A6 (0.61) | SLC22A6AKR1B1LMNAGPR84PPARG | |
| Adipic Acid SCHEMBL5875010 | 0.94 | AKR1B1 (0.62) | SLC22A6AKR1B1LMNAGPR84PPARG | |
| Adipic Acid SCHEMBL5875018 | 0.94 | AKR1B1 (0.62) | SLC22A6AKR1B1LMNAGPR84PPARG | |
| Azelaic Acid SCHEMBL17140336 | 0.92 | GPR84 (0.64) | SLC22A6AKR1B1LMNAGPR84PPARG | |
| SCHEMBL10891072 | 0.92 | GPR84 (0.64) | SLC22A6AKR1B1LMNAGPR84PPARG | |
| SCHEMBL10891070 | 0.92 | GPR84 (0.64) | SLC22A6AKR1B1LMNAGPR84PPARG | |
| Sebacic Acid SCHEMBL5874634 | 0.92 | GPR84 (0.64) | SLC22A6AKR1B1LMNAGPR84PPARG | |
| Sebacic Acid SCHEMBL5874637 | 0.92 | GPR84 (0.64) | SLC22A6AKR1B1LMNAGPR84PPARG | |
| Valeric Acid SCHEMBL3414377 | 0.90 | AKR1B1 (0.64) | SLC22A6AKR1B1GPR84PPARGPPARD | |
| Succinic Acid SCHEMBL5874898 | 0.88 | LMNA (0.56) | SLC22A6AKR1B1LMNAGPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088548-B2 | Bottom antireflective coating compositions | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2012-01-03 | — | — | US | disclosed |
| EP-2212273-A2 | BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS | AZ Electronic Materials USA Corp. (US) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009053832-A2 | BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS | AZ ELECTRONIC MATERIALS USA CORP. (DE) | 2009-04-30 | — | — | WO | disclosed |
| US-20090104559-A1 | Bottom Antireflective Coating Compositions | MERCK PATENT GMBH (DE) | 2009-04-23 | — | — | US | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| US-5567597-A | DIAGNOSING THE DISEASE BY DETECTING, MEASURING THE LIPASE, PHOSPHOLIPASE, ESTERASE, PROTEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-10-22 | — | — | US | disclosed |
| US-5427919-A | Therapy, analysis substrates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-06-27 | — | — | US | disclosed |
| US-5352673-A | Administering to inactivate or inhibit phospholipase A | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE A CORP. OF CALIFORNIA | 1994-10-04 | — | — | US | disclosed |
| US-5308766-A | Hydrolytic enzyme inhibitors/inactivators and methods for using same | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-05-03 | — | — | US | disclosed |
| WO-1992022289-A1 | NOVEL PHOSPHOLIPASE A2 INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090104559-A1 | Bottom Antireflective Coating Compositions | SDC2, S100A9, MYH9 | SLC22A6 1567/4885AKR1B1 3022/4885LMNA 686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.