SCHEMBL21972040

SCHEMBL21972040

CC(C)(C)c1c(-c2ccccc2)cccc1-n1c2ccccc2c2cccc(-c3ccccc3)c21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DUSP3 P51452 1/20 0.40
KDM4E B2RXH2 2/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ALDH1A1 P00352 3/20 0.36
MAPK14 Q16539 1/20 0.35
ALKBH5 Q6P6C2 1/20 0.34
FTO Q9C0B1 1/20 0.34
HSD17B10 Q99714 1/20 0.34
HSD11B1 P28845 1/20 0.33
METAP2 P50579 1/20 0.33
HRH4 Q9H3N8 1/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MAP4K4 O95819 1/20 0.32
CSF1R P07333 1/20 0.32
FGFR1 P11362 1/20 0.32
PDGFRA P16234 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25027466 0.94 NR1H4 (0.38) DUSP3KDM4EALDH1A1KMT2AMEN1
SCHEMBL25456821 0.94 L3MBTL1 (0.36) DUSP3L3MBTL1ALDH1A1MAPK14ALKBH5
SCHEMBL20968533 0.93 ALDH1A1 (0.41) DUSP3KDM4EATML3MBTL1ALDH1A1
SCHEMBL21972042 0.91 DUSP3 (0.34) DUSP3KDM4EATML3MBTL1ALDH1A1
SCHEMBL25456499 0.91 NPC1 (0.38) DUSP3L3MBTL1ALDH1A1KMT2AENPP1
SCHEMBL25456501 0.91 DUSP3 (0.34) DUSP3KDM4EATML3MBTL1ALDH1A1
SCHEMBL21972041 0.91 DUSP3 (0.37) DUSP3KDM4EATML3MBTL1ALDH1A1
SCHEMBL25470254 0.87 DUSP3 (0.36) DUSP3ALDH1A1ALKBH5FTO
SCHEMBL21972185 0.86 DUSP3 (0.40) DUSP3KDM4EATML3MBTL1ALDH1A1
SCHEMBL25491124 0.85 NR1H4 (0.34) DUSP3KDM4EALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-11864458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-01-02 US disclosed
US-11864458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-01-02 US disclosed
US-11832510-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-11832510-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-20230371360-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230371360-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20220069241-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-03-03 US disclosed
US-20210292351-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-09-23 US disclosed
US-20210253446-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-08-19 US disclosed
US-20210175443-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-06-10 US disclosed
US-20210104690-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-04-08 US disclosed
US-20210066622-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-03-04 US disclosed
US-20210050532-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-02-18 US disclosed
US-20200411775-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-12-31 US disclosed
US-20200220090-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-07-09 US disclosed
US-20200140471-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210292351-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OSBP, OCIAD1 DUSP3 2785/4885KDM4E 3816/4885ATM 2995/4885
US-11832510-B2 Organic electroluminescent materials and devices OSBP, OCIAD2, OCIAD1 DUSP3 4035/4885KDM4E 3847/4885ATM 3881/4885
US-20210066622-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, JUND DUSP3 4599/4885KDM4E 2540/4885ATM 4095/4885
US-20230371360-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CHRM1, L1CAM, SOD1 DUSP3 4773/4885KDM4E 1644/4885ATM 3119/4885
US-20200140471-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 DUSP3 4598/4885KDM4E 3928/4885ATM 3912/4885
US-11864458-B2 Organic electroluminescent materials and devices RAP1A, L1CAM, SOD1 DUSP3 4095/4885KDM4E 1807/4885ATM 2489/4885
US-20200220090-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 DUSP3 4613/4885KDM4E 2142/4885ATM 2307/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG DUSP3 4707/4885KDM4E 3179/4885ATM 4355/4885
US-20220069241-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CHRM1, LBR, CNKSR1 DUSP3 4534/4885KDM4E 1449/4885ATM 2246/4885
US-20210050532-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EPCAM, LEF1 DUSP3 4641/4885KDM4E 3600/4885ATM 2662/4885
US-20200411775-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD2, OCIAD1 DUSP3 4035/4885KDM4E 3847/4885ATM 3881/4885
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, ROS1 DUSP3 3911/4885KDM4E 2950/4885ATM 3559/4885
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, OXSR1 DUSP3 4495/4885KDM4E 4005/4885ATM 3650/4885
US-20210175443-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OTC DUSP3 4610/4885KDM4E 1544/4885ATM 3881/4885
US-20210104690-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RAP1A, L1CAM, SOD1 DUSP3 4095/4885KDM4E 1807/4885ATM 2489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.