SCHEMBL21972041

SCHEMBL21972041

CC(C)(C)c1cccc(-n2c3ccccc3c3cccc(-c4ccccc4)c32)c1C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DUSP3 P51452 1/20 0.37
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 2/20 0.33
MAPK14 Q16539 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HSD17B10 Q99714 1/20 0.32
ALKBH5 Q6P6C2 1/20 0.32
FTO Q9C0B1 1/20 0.32
HSD11B1 P28845 2/20 0.31
TRPA1 O75762 1/20 0.31
KIF11 P52732 1/20 0.31
METAP2 P50579 1/20 0.31
HRH4 Q9H3N8 1/20 0.30
RORC P51449 1/20 0.30
KMT2A Q03164 2/20 0.30
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
MAP4K4 O95819 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21972185 0.91 DUSP3 (0.40) DUSP3ALDH1A1KDM4EMAPK14ATM
SCHEMBL21972040 0.91 DUSP3 (0.40) DUSP3ALDH1A1KDM4EMAPK14ATM
SCHEMBL23490981 0.88 DUSP3 (0.34) DUSP3TRPA1
SCHEMBL26254029 0.87 DUSP3 (0.37) DUSP3ALDH1A1KDM4EMAPK14ATM
SCHEMBL25027466 0.85 NR1H4 (0.38) DUSP3ALDH1A1KDM4EKIF11KMT2A
SCHEMBL25456821 0.85 L3MBTL1 (0.36) DUSP3ALDH1A1MAPK14L3MBTL1ALKBH5
SCHEMBL21972209 0.84 ALDH1A1 (0.41) ALDH1A1KDM4EATML3MBTL1ALKBH5
SCHEMBL24311381 0.84 DUSP3 (0.38) DUSP3ALDH1A1KDM4EMAPK14ATM
SCHEMBL25719832 0.84 DUSP3 (0.35) DUSP3ALDH1A1KDM4EMAPK14ATM
SCHEMBL20968533 0.83 ALDH1A1 (0.41) DUSP3ALDH1A1KDM4EMAPK14ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-11864458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-01-02 US disclosed
US-11864458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-01-02 US disclosed
US-20230371360-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230357296-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 US disclosed
US-11802136-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-31 US disclosed
US-20220402953-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSITY DISPLAY CORPORATION (US) 2022-12-22 US disclosed
US-20220396596-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-12-15 US disclosed
US-20220393117-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-12-08 US disclosed
US-20220153769-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-19 US disclosed
US-20210175443-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-06-10 US disclosed
US-20210104690-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-04-08 US disclosed
US-20210066622-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-03-04 US disclosed
US-20210050532-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-02-18 US disclosed
US-20200220090-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-07-09 US disclosed
US-20200140471-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (17 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220393117-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NPY1R, NPY2R, KISS1R DUSP3 3270/4885ALDH1A1 1485/4885KDM4E 1106/4885
US-20210066622-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, JUND DUSP3 4599/4885ALDH1A1 3477/4885KDM4E 2540/4885
US-20220396596-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, DRD3 DUSP3 3778/4885ALDH1A1 1664/4885KDM4E 3611/4885
US-20230371360-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CHRM1, L1CAM, SOD1 DUSP3 4773/4885ALDH1A1 831/4885KDM4E 1644/4885
US-20230357296-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, OXER1, LBR DUSP3 4841/4885ALDH1A1 1046/4885KDM4E 4190/4885
US-20200140471-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 DUSP3 4598/4885ALDH1A1 268/4885KDM4E 3928/4885
US-11864458-B2 Organic electroluminescent materials and devices RAP1A, L1CAM, SOD1 DUSP3 4095/4885ALDH1A1 165/4885KDM4E 1807/4885
US-20200220090-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 DUSP3 4613/4885ALDH1A1 612/4885KDM4E 2142/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG DUSP3 4707/4885ALDH1A1 149/4885KDM4E 3179/4885
US-20210050532-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EPCAM, LEF1 DUSP3 4641/4885ALDH1A1 196/4885KDM4E 3600/4885
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, ROS1 DUSP3 3911/4885ALDH1A1 569/4885KDM4E 2950/4885
US-20220402953-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP DUSP3 4835/4885ALDH1A1 134/4885KDM4E 2986/4885
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, OXSR1 DUSP3 4495/4885ALDH1A1 728/4885KDM4E 4005/4885
US-20210175443-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OTC DUSP3 4610/4885ALDH1A1 402/4885KDM4E 1544/4885
US-20210104690-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RAP1A, L1CAM, SOD1 DUSP3 4095/4885ALDH1A1 165/4885KDM4E 1807/4885
US-20220153769-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ODC1, OCIAD1, OCIAD2 DUSP3 4844/4885ALDH1A1 102/4885KDM4E 2154/4885
US-11802136-B2 Organic electroluminescent materials and devices OSBP, OCIAD1, OCIAD2 DUSP3 4598/4885ALDH1A1 268/4885KDM4E 3928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.