SCHEMBL21972230

SCHEMBL21972230

CC(C)(C)c1cc(-c2ccc3oc4cccc(-c5ccccc5)c4c3c2C(C)(C)C)cc(C(C)(C)C)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RXRA P19793 4/20 0.37
▸ RXRB P28702 4/20 0.37
▸ CYP26B1 Q9NR63 2/20 0.33
▸ RXRG P48443 2/20 0.33
▸ CYP26A1 O43174 1/20 0.33
▸ RAB9A P51151 3/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ ALDH1A1 P00352 3/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ PLA2G1B P04054 1/20 0.32
▸ NFKB1 P19838 1/20 0.32
▸ CASP3 P42574 1/20 0.32
▸ NFKB2 Q00653 1/20 0.32
▸ RELA Q04206 1/20 0.32
▸ SENP8 Q96LD8 1/20 0.32
▸ SENP7 Q9BQF6 1/20 0.32
▸ SENP6 Q9GZR1 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ ATG4B Q9Y4P1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21972047 1.00 RXRA (0.37) RXRARXRBCYP26B1RXRGCYP26A1
SCHEMBL24433630 0.95 RXRA (0.34) RXRARXRBCYP26B1RXRGCYP26A1
SCHEMBL21972236 0.90 RAB9A (0.34) RAB9AMEN1KMT2AALDH1A1MAPT
SCHEMBL26194975 0.90 ALDH1A1 (0.40) RXRARXRBALDH1A1MAPTMAOB
SCHEMBL25768506 0.89 CHEK1 (0.42) RXRARXRBRAB9AALDH1A1NPC1
SCHEMBL24433579 0.88 RXRA (0.38) RXRARXRBCYP26B1RXRGCYP26A1
SCHEMBL24776075 0.88 ALDH1A1 (0.34) RAB9AMEN1KMT2AALDH1A1MAPT
SCHEMBL25523477 0.88 RXRA (0.38) RXRARXRBCYP26B1RXRGCYP26A1
SCHEMBL25456534 0.84 CHEK1 (0.45) RAB9AMEN1KMT2AALDH1A1NPC1
SCHEMBL25771526 0.84 ALDH1A1 (0.38) RAB9AALDH1A1NPC1NFKB1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 — — US disclosed
US-11864458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-01-02 — — US disclosed
US-11864458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-01-02 — — US disclosed
US-20230371360-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 — — US disclosed
US-20230371360-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 — — US disclosed
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 — — US disclosed
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 — — US disclosed
US-20230357296-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 — — US disclosed
US-11802136-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-31 — — US disclosed
US-11802136-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-31 — — US disclosed
US-20230140064-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-04 — — US disclosed
US-20230049161-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-02-16 — — US disclosed
US-20230041530-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-02-09 — — US disclosed
US-20230002417-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-01-05 — — US disclosed
US-20230002430-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-01-05 — — US disclosed
US-20220402953-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSITY DISPLAY CORPORATION (US) 2022-12-22 — — US disclosed
US-20210104690-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-04-08 — — US disclosed
US-20210066622-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-03-04 — — US disclosed
US-20200220090-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-07-09 — — US disclosed
US-20200140471-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-05-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (17 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210066622-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, JUND RXRA 2660/4885RXRB 3052/4885CYP26B1 4831/4885
US-20230371360-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CHRM1, L1CAM, SOD1 RXRA 621/4885RXRB 562/4885CYP26B1 3910/4885
US-20230357296-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, OXER1, LBR RXRA 138/4885RXRB 160/4885CYP26B1 3319/4885
US-20200140471-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 RXRA 1861/4885RXRB 1833/4885CYP26B1 591/4885
US-11864458-B2 Organic electroluminescent materials and devices RAP1A, L1CAM, SOD1 RXRA 248/4885RXRB 262/4885CYP26B1 2740/4885
US-20230002417-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 RXRA 2845/4885RXRB 2853/4885CYP26B1 1154/4885
US-20200220090-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 RXRA 3298/4885RXRB 3278/4885CYP26B1 3117/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG RXRA 1472/4885RXRB 1490/4885CYP26B1 1850/4885
US-20230002430-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CHRM1, L1CAM, SOD1 RXRA 612/4885RXRB 562/4885CYP26B1 3902/4885
US-20230140064-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CCND3 RXRA 420/4885RXRB 295/4885CYP26B1 2678/4885
US-20230049161-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, AOC2, OCIAD1 RXRA 1141/4885RXRB 740/4885CYP26B1 2490/4885
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, ROS1 RXRA 894/4885RXRB 958/4885CYP26B1 4099/4885
US-20220402953-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP RXRA 2923/4885RXRB 2880/4885CYP26B1 2562/4885
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, OXSR1 RXRA 262/4885RXRB 336/4885CYP26B1 3127/4885
US-20210104690-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RAP1A, L1CAM, SOD1 RXRA 248/4885RXRB 262/4885CYP26B1 2740/4885
US-11802136-B2 Organic electroluminescent materials and devices OSBP, OCIAD1, OCIAD2 RXRA 1861/4885RXRB 1833/4885CYP26B1 591/4885
US-20230041530-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CHRM1 RXRA 142/4885RXRB 163/4885CYP26B1 3617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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