SCHEMBL2197474

SCHEMBL2197474

N#CNc1ccc(N)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.42
ALDH1A1 P00352 5/20 0.42
CYP3A4 P08684 4/20 0.42
HTT P42858 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
ALOX12 P18054 1/20 0.42
CYP2C19 P33261 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
RAB9A P51151 3/20 0.41
RAD52 P43351 1/20 0.39
APP P05067 2/20 0.38
TDP1 Q9NUW8 3/20 0.37
ALOX15 P16050 3/20 0.37
TP53 P04637 2/20 0.37
HSD17B10 Q99714 2/20 0.37
NR4A1 P22736 1/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8985134 0.86 ALDH1A1 (0.32) MAPTALDH1A1CYP1A2CA1CA2
SCHEMBL1712020 0.74 MAPT (0.46) MAPTALDH1A1CYP3A4HTTCYP1A2
SCHEMBL17107320 0.74 ALDH1A1 (0.38) MAPTALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL15546400 0.74 CA1 (0.38) APPCA1CA2CA9
SCHEMBL9463504 0.74 CA2 (0.46) MAPTALDH1A1CYP3A4ALOX12L3MBTL1
SCHEMBL10804520 0.74 ALDH1A1 (0.46) MAPTALDH1A1HTTALOX12MEN1
SCHEMBL2836022 0.74 MAPT (0.44) MAPTALDH1A1HTTMEN1KMT2A
SCHEMBL8985157 0.73 ALDH1A1 (0.32) ALDH1A1
SCHEMBL6158941 0.73 ALDH1A1 (0.44) MAPTALDH1A1MEN1KMT2ARAB9A
Cyanamide SCHEMBL28652657 0.73 ALDH1A1 (0.40) MAPTALDH1A1HTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115558135-A High-heat-resistance polyimide film with cross-linked structure, preparation method and application 大连理工大学 2023-01-03 CN claimed
EP-3184675-B1 HIGH-STRENGTH COPOLYMERIZED ARAMID FIBER AND PREPARING METHOD THEREFOR KOLON INC (KR) 2019-07-24 EP claimed
CN-106661774-B High intensity copolymerization aramid fibre and preparation method thereof 可隆工业株式会社 2019-06-21 CN claimed
EP-3091107-B1 COPOLYMERIZED ARAMID DOPE-DYED YARN AND METHOD FOR PREPARING SAME KOLON INC (KR) 2019-02-13 EP claimed
US-20180195207-A1 COPOLYMERIZED ARAMID DOPE-DYED YARN AND METHOD FOR PREPARING SAME KOLON INDUSTRIES, INC. (KR) 2018-07-12 US claimed
US-20170241048-A1 HIGH-STRENGTH COPOLYMERIZED ARAMID FIBER AND PREPARING METHOD THEREFOR KOLON INDUSTRIES, INC. (KR) 2017-08-24 US claimed
EP-3184675-A1 HIGH-STRENGTH COPOLYMERIZED ARAMID FIBER AND PREPARING METHOD THEREFOR Kolon Industries, Inc. (KR) 2017-06-28 EP claimed
EP-3091107-A1 COPOLYMERIZED ARAMID DOPE-DYED YARN AND METHOD FOR PREPARING SAME Kolon Industries, Inc. (KR) 2016-11-09 EP claimed
CN-115558135-A High-heat-resistance polyimide film with cross-linked structure, preparation method and application 大连理工大学 2023-01-03 CN disclosed
EP-3184675-B1 HIGH-STRENGTH COPOLYMERIZED ARAMID FIBER AND PREPARING METHOD THEREFOR KOLON INC (KR) 2019-07-24 EP disclosed
CN-106661774-B High intensity copolymerization aramid fibre and preparation method thereof 可隆工业株式会社 2019-06-21 CN disclosed
CN-106661774-B High intensity copolymerization aramid fibre and preparation method thereof 可隆工业株式会社 2019-06-21 CN disclosed
EP-3091107-B1 COPOLYMERIZED ARAMID DOPE-DYED YARN AND METHOD FOR PREPARING SAME KOLON INC (KR) 2019-02-13 EP disclosed
US-20180223452-A1 HIGHLY ELASTIC COPOLYMERIZED ARAMID FIBERS KOLON INDUSTRIES, INC. (KR) 2018-08-09 US disclosed
WO-2014104648-A1 METHOD OF DRY-SPINNING PARA-ARAMID FIBER KOLON INDUSTRIES, INC. (KR) 2014-07-03 WO disclosed
US-7977028-B2 Photosensitive resin composition and adhesion promoter TORAY INDUSTRIES, INC. (JP) 2011-07-12 US disclosed
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER TORAY INDUSTRIES, INC. (JP) 2009-05-14 US disclosed
EP-1909142-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES, INC. (JP) 2008-04-09 EP disclosed
US-6143917-A FROM A DIARYL CARBONATE AND AN AMINE COMPOUND HAVING AT LEAST ONE HYDROGEN ATOM LOCATED AT AN N-POSITION UNDER MODERATE CONDITIONS AT A HIGH REACTION RATE WITH A HIGH SELECTIVITY AND WITH A HIGH YIELD UBE INDUSTRIES, LTD. (JP) 2000-11-07 US disclosed
EP-0902014-A1 PROCESS FOR PRODUCING ARYL CARBAMATES UBE INDUSTRIES LIMITED (JP) 1999-03-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER PCNA, TERB1, SMC2 MAPT 1072/4885ALDH1A1 1144/4885CYP3A4 4337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.