Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyanamide SCHEMBL28652657 | 0.93 | ALDH1A1 (0.40) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL8985134 | 0.86 | ALDH1A1 (0.32) | MAPTALDH1A1CA1CA2 | |
| SCHEMBL31070132 | 0.78 | CYP1A2 (0.40) | HTT | |
| SCHEMBL8829718 | 0.74 | TSHR (0.42) | MAPTLMNATSHRALDH1A1GAA | |
| SCHEMBL15546400 | 0.74 | CA1 (0.38) | CA1CA2CNR1 | |
| SCHEMBL4756760 | 0.74 | LMNA (0.42) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL3090716 | 0.74 | LMNA (0.42) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL9463504 | 0.74 | CA2 (0.46) | MAPTLMNATSHRALDH1A1GAA | |
| SCHEMBL2197474 | 0.74 | MAPT (0.42) | MAPTLMNATSHRHTTALDH1A1 | |
| SCHEMBL1486303 | 0.74 | NPC1 (0.43) | MAPTLMNATSHRHTTNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768824-B | Imide azole heterocyclic compound and application thereof | 华南农业大学 | 2025-06-10 | — | — | CN | disclosed |
| CN-116768824-A | Imide azole heterocyclic compound and application thereof | 华南农业大学 | 2023-09-19 | — | — | CN | disclosed |
| EP-2166838-B1 | TOPICAL DENTAL SOLUTION OF CHLORHEXIDINE IN SUMATRA BENZOIN BP/EP AND METHODS OF MANUFACTURING AND EVALUATING SAME | CHX TECH INC (CA) | 2018-10-24 | — | — | EP | disclosed |
| EP-2245020-B1 | THIAZOLYLIDINE UREA AND AMIDE DERIVATIVES AND METHODS OF USE THEREOF | ABBVIE INC (US) | 2014-01-15 | — | — | EP | disclosed |
| US-8383657-B2 | Thiazolylidine urea and amide derivatives and methods of use thereof | ABBOTT LABORATORIES (US) | 2013-02-26 | — | — | US | disclosed |
| CN-101903364-A | Thiazoline urea and amide derivatives and methods of use thereof | ABBOTT LAB | 2010-12-01 | — | — | CN | disclosed |
| EP-2245020-A2 | THIAZOLYLIDINE UREA AND AMIDE DERIVATIVES AND METHODS OF USE THEREOF | Abbott Laboratories (US) | 2010-11-03 | — | — | EP | disclosed |
| EP-2166838-A2 | TOPICAL DENTAL SOLUTION OF CHLORHEXIDINE IN SUMATRA BENZOIN BP/EP AND METHODS OF MANUFACTURING AND EVALUATING SAME | CHX Technologies Inc. (CA) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009086163-A2 | THIAZOLYLIDINE UREA AND AMIDE DERIVATIVES AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2009-07-09 | — | — | WO | disclosed |
| US-20090163470-A1 | THIAZOLYLIDINE UREA AND AMIDE DERIVATIVES AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2009-06-25 | — | — | US | disclosed |
| US-5847006-A | Therapeutic guanidines | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-12-08 | — | — | US | disclosed |
| EP-0746316-A4 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE INC (US) | 1997-12-10 | — | — | EP | disclosed |
| EP-0746316-A1 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1996-12-11 | — | — | EP | disclosed |
| WO-1995014467-A1 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1995-06-01 | — | — | WO | disclosed |
| US-4791229-A | WITH ACETIC ACID SOLVENT AND AUXILIARY BASE | BAYER AKTIENGESELLSCHAFT (DE) | 1988-12-13 | — | — | US | disclosed |
| EP-0220584-A2 | Process for the preparation of aryl cyanamides | BAYER AG (DE) | 1987-05-06 | — | — | EP | disclosed |
| US-4496727-A | ORGANIC PIGMENTS; PLASTICS; LACQUERS; INKS; COATINGS; COLOR FASTNESS | CIBA-GEIGY CORPORATION (US) | 1985-01-29 | — | — | US | disclosed |
| US-4110445-A | METHOD FOR ANTAGONIZING ALDOSTERONIC ACTION AND INDUCING DIURESIS BY ADMINISTERING A TETRASUBSTITUTED IMIDAZOLIDINE | AMERICAN CYANAMID COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-4051256-A | ANTIRHINOVIRUS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (EN) | 1977-09-27 | — | — | US | disclosed |
| US-4044021-A | Tetrasubstituted imidazolidine diuretics useful in the treatment of hyperaldosteronism | AMERICAN CYANAMID COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163470-A1 | THIAZOLYLIDINE UREA AND AMIDE DERIVATIVES AND METHODS OF USE THEREOF | NMUR1, NMUR2, PAM | MAPT 465/4885LMNA 2279/4885TSHR 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.