SCHEMBL2197479

SCHEMBL2197479

N#CNc1ccccc1N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 7/20 0.46
MAPT P10636 6/20 0.46
KDM4E B2RXH2 6/20 0.46
ALDH1A1 P00352 4/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
LMNA P02545 2/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
CYP2D6 P10635 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.43
ALOX15 P16050 2/20 0.43
HPGD P15428 2/20 0.43
TP53 P04637 1/20 0.43
APP P05067 1/20 0.43
SNCA P37840 1/20 0.43
BLM P54132 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CYP3A4 P08684 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11050237 0.82 TSHR (0.36) GAAKDM4EHPGDHSD17B10MAPK1
SCHEMBL3859560 0.80 GAA (0.42) GAAMAPTKDM4EALDH1A1MEN1
SCHEMBL1938533 0.76 MAPT (0.46) GAAMAPTKDM4EALDH1A1MEN1
SCHEMBL3168133 0.71 ALDH1A1 (0.43) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL22150361 0.71 MAPT (0.46) GAAMAPTKDM4EALDH1A1MEN1
SCHEMBL6584880 0.71 SIGMAR1 (0.36) KDM4EHPGDHSD17B10
SCHEMBL8872909 0.71 MAPT (0.48) GAAMAPTKDM4EALDH1A1MEN1
SCHEMBL3184890 0.71 RAB9A (0.45) GAAALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL27884179 0.71 KDM4E (0.52) GAAKDM4EALDH1A1MEN1KMT2A
SCHEMBL9463502 0.71 RAB9A (0.41) GAAMAPTKDM4EALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115558135-A High-heat-resistance polyimide film with cross-linked structure, preparation method and application 大连理工大学 2023-01-03 CN claimed
CN-115558135-B High heat-resistant polyimide film with cross-linked structure, preparation method and application 大连理工大学 2024-10-08 CN disclosed
CN-115558135-A High-heat-resistance polyimide film with cross-linked structure, preparation method and application 大连理工大学 2023-01-03 CN disclosed
CN-107954939-B N under a kind of microwave radiation, the method for the thio formyl chloride derivatives catalysis synthesizing benzimidazole derivative of N- dimethylamino 福建医科大学 2019-09-17 CN disclosed
CN-108341783-A A kind of iron catalysis N, the method for the thio formyl chlorine derivative synthesizing benzimidazole derivative of N- dimethylaminos 福建医科大学 2018-07-31 CN disclosed
EP-1909142-B1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES (JP) 2015-06-24 EP disclosed
US-7977028-B2 Photosensitive resin composition and adhesion promoter TORAY INDUSTRIES, INC. (JP) 2011-07-12 US disclosed
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER TORAY INDUSTRIES, INC. (JP) 2009-05-14 US disclosed
EP-1909142-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES, INC. (JP) 2008-04-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER PCNA, TERB1, SMC2 GAA 2083/4885MAPT 1072/4885KDM4E 151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.