Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PRKDC | P78527 | 2/20 | 0.55 |
| ▸ | XRCC6 | P12956 | 1/20 | 0.54 |
| ▸ | XRCC5 | P13010 | 1/20 | 0.54 |
| ▸ | SORD | Q00796 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30903262 | 0.86 | ELANE (0.57) | ELANESORDGAAKMT2ALMNA | |
| SCHEMBL31472604 | 0.86 | ELANE (0.61) | ELANEALDH1A1SORDGAAKMT2A | |
| SCHEMBL5021493 | 0.86 | ELANE (0.61) | ELANEALDH1A1SORDGAAKMT2A | |
| SCHEMBL1981175 | 0.84 | ELANE (0.62) | ELANEALDH1A1SORDGAAKMT2A | |
| SCHEMBL1713373 | 0.84 | SORD (0.55) | ELANESORDGAAKMT2ALMNA | |
| SCHEMBL5021503 | 0.84 | ELANE (0.62) | ELANEALDH1A1SORDGAAKMT2A | |
| SCHEMBL2624458 | 0.84 | SORD (0.58) | ELANESORDGAAKMT2ALMNA | |
| SCHEMBL31473673 | 0.83 | LMNA (0.57) | ALDH1A1SORDGAAKMT2ALMNA | |
| SCHEMBL2201069 | 0.83 | CHRNA7 (0.54) | ELANESORDGAAKMT2ALMNA | |
| SCHEMBL195554 | 0.81 | HTR6 (0.53) | ELANEALDH1A1SORDGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025906-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | SUNDANCE BIOSCIENCES, INC. | 2024-01-25 | — | — | US | disclosed |
| US-20220127263-A1 | Novel Compounds for the Treatment, Alleviation or Prevention of Disorders Associated with Tau Aggregates | AC IMMUNE SA (CH) | 2022-04-28 | — | — | US | disclosed |
| US-20210371992-A1 | ELECTROCHEMICAL ORGANIC REACTION SETUP AND METHODS | PIRAMAL PHARMA LIMITED (IN) | 2021-12-02 | — | — | US | disclosed |
| US-11136317-B2 | NADPH oxidase 4 inhibitors | ACTELION PHARMACEUTICALS LTD (CH) | 2021-10-05 | — | — | US | disclosed |
| US-20200165235-A1 | NADPH OXIDASE 4 INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2020-05-28 | — | — | US | disclosed |
| CN-103333131-A | Preparation method of 2-aminobenzoxazole compound | SUZHOU OST ADVANCED MATERIALS CO LTD | 2013-10-02 | — | — | CN | disclosed |
| CN-102596958-A | 2' -fluoro CARBA-nucleoside analogs for antiviral treatment | GILEAD SCIENCES INC | 2012-07-18 | — | — | CN | disclosed |
| CN-101326454-B | Method for manufacturing polarizing plate, polarizing plate and liquid crystal display device | KONICA MINOLTA OPTO INC | 2010-11-03 | — | — | CN | disclosed |
| CN-101326454-A | Method for manufacturing polarizing plate, polarizing plate and liquid crystal display device | KONICA MINOLTA OPTO INC (JP) | 2008-12-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127263-A1 | Novel Compounds for the Treatment, Alleviation or Prevention of Disorders Associated with Tau Aggregates | MAPT, MAP1LC3A, MAP1LC3B | ELANE 3545/4885ALDH1A1 3543/4885POLB 2923/4885 |
| US-20200165235-A1 | NADPH OXIDASE 4 INHIBITORS | NOX4, NOX1, CYBB | ELANE 428/4885ALDH1A1 176/4885POLB 1792/4885 |
| US-11136317-B2 | NADPH oxidase 4 inhibitors | NOX4, NOX1, CYBB | ELANE 428/4885ALDH1A1 176/4885POLB 1792/4885 |
| US-20240025906-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | TYK2, JAK1, JAK3 | ELANE 4593/4885ALDH1A1 4807/4885POLB 3568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.