SCHEMBL2198735

SCHEMBL2198735

CCCCCCCCC=CCCCCCCCC(=O)OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ DGKA P23743 1/20 0.48
▸ LPAR1 Q92633 1/20 0.47
▸ TLR4 O00206 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12427210 1.00 DGKA (0.48) DGKALPAR1TLR4
SCHEMBL23432460 1.00 DGKA (0.48) DGKALPAR1TLR4
SCHEMBL2198730 1.00 DGKA (0.48) DGKALPAR1TLR4
SCHEMBL13240137 1.00 DGKA (0.48) DGKALPAR1TLR4
SCHEMBL2198741 1.00 DGKA (0.48) DGKALPAR1TLR4
SCHEMBL13265734 0.99 DGKA (0.47) DGKALPAR1TLR4
SCHEMBL13240138 0.99 DGKA (0.47) DGKALPAR1TLR4
SCHEMBL2201777 0.96 — —
SCHEMBL12430969 0.96 — —
SCHEMBL2493311 0.96 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2861205-B1 COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A GLUCOSE AND FATTY ACID ESTER. OREAL (FR) 2017-12-06 — — EP claimed
EP-1837341-B1 Derivative of glucose and vitamin F, compositions containing it, its uses to improve the state of hair OREAL (FR) 2011-08-03 — — EP claimed
US-7763587-B2 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. (FR) 2010-07-27 — — US claimed
US-20100143279-A1 COSMETIC/DERMATOLOGICAL COMPOSITIONS COMPRISING A DERIVATIVE OF GLUCOSE AND OF VITAMIN F AND A SPECIFIC SURFACTANT L'OREAL (FR) 2010-06-10 — — US claimed
US-20090149396-A1 DERIVATIVE OF GLUCOSE AND VITAMIN F, COMPOSITIONS COMPRISING IT, USES AND PREPARATION PROCESS L'OREAL S.A. 2009-06-11 — — US claimed
EP-1837341-A1 Derivative of glucose and vitamin F, compositions containing it, its uses and its preparation L'Oréal (FR) 2007-09-26 — — EP claimed
EP-1371658-B1 Derivative of glucose and vitamin F, compositions containing it, its uses and its preparation OREAL (FR) 2007-09-12 — — EP claimed
US-20070123471-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. 2007-05-31 — — US claimed
US-20060177403-A1 Cosmetic/dermatological compositions comprising a derivative of glucose and of vitamin F and A specific surfactant L'OREAL (FR) 2006-08-10 — — US claimed
US-20060165630-A1 Use of amide or ester of sugar and of fatty acid, for treating and/or preventing dry skin L'OREAL (FR) 2006-07-27 — — US claimed
US-20060166902-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. 2006-07-27 — — US claimed
US-20060106209-A1 Novel process for the preparation of o-acylated glucose derivatives L'OREAL (FR) 2006-05-18 — — US claimed
EP-1551362-A2 USE OF AMIDE OR ESTER OF SUGAR AND OF FATTY ACID, FOR TREATING AND/OR PREVENTING DRY SKIN. L'OREAL (FR) 2005-07-13 — — EP claimed
US-20040192906-A1 Novel process for the preparation of O-acylated glucose derivatives L'OREAL (FR) 2004-09-30 — — US claimed
EP-1454913-A1 Method for the synthesis of O-acylated derivatives of glucose L'OREAL (FR) 2004-09-08 — — EP claimed
WO-2004034958-A2 USE OF AMIDE OR ESTER OF SUGAR AND OF FATTY ACID, FOR TREATING AND/OR PREVENTING DRY SKIN L'OREAL (FR) 2004-04-29 — — WO claimed
US-20040038912-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. (FR) 2004-02-26 — — US claimed
EP-1371658-A1 Derivative of glucose and vitamin F, compositions containing it, its uses and its preparation L'OREAL (FR) 2003-12-17 — — EP claimed
EP-1688128-B1 Method for treating keratinic fibres and the scalp with a composition containing a derivative of glucose and vitamin F L'ORÉAL (FR) 2018-03-07 — — EP disclosed
EP-1371658-A1 Derivative of glucose and vitamin F, compositions containing it, its uses and its preparation L'OREAL (FR) 2003-12-17 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060166902-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process FASN, ELOVL6, ACSL6 DGKA 584/4885LPAR1 1124/4885TLR4 2674/4885
US-20060177403-A1 Cosmetic/dermatological compositions comprising a derivative of glucose and of vitamin F and A specific surfactant HKDC1, ADH1B, HK1 DGKA 751/4885LPAR1 1384/4885TLR4 3459/4885
US-20060106209-A1 Novel process for the preparation of o-acylated glucose derivatives SLC2A4, SLC2A3, SLC5A2 DGKA 672/4885LPAR1 4201/4885TLR4 2746/4885
US-20100143279-A1 COSMETIC/DERMATOLOGICAL COMPOSITIONS COMPRISING A DERIVATIVE OF GLUCOSE AND OF VITAMIN F AND A SPECIFIC SURFACTANT HKDC1, ADH1B, HK1 DGKA 751/4885LPAR1 1384/4885TLR4 3459/4885
US-20040192906-A1 Novel process for the preparation of O-acylated glucose derivatives SLC2A4, SLC2A3, SLC5A2 DGKA 672/4885LPAR1 4201/4885TLR4 2746/4885
US-20090149396-A1 DERIVATIVE OF GLUCOSE AND VITAMIN F, COMPOSITIONS COMPRISING IT, USES AND PREPARATION PROCESS FASN, ELOVL6, FADS2 DGKA 552/4885LPAR1 984/4885TLR4 2700/4885
US-20070123471-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process FASN, ELOVL6, ACSL6 DGKA 584/4885LPAR1 1124/4885TLR4 2674/4885
US-20040038912-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process FASN, ELOVL6, ACSL6 DGKA 584/4885LPAR1 1124/4885TLR4 2674/4885
US-20060165630-A1 Use of amide or ester of sugar and of fatty acid, for treating and/or preventing dry skin CUTA, SCD5, SCD DGKA 504/4885LPAR1 454/4885TLR4 685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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