SCHEMBL21990258

SCHEMBL21990258

Oc1cc(N(c2ccccc2)c2ccccc2)c2ccccc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 1/20 0.52
ALDH1A1 P00352 3/20 0.50
KDM4E B2RXH2 2/20 0.50
MEN1 O00255 2/20 0.50
HPGD P15428 2/20 0.50
KMT2A Q03164 2/20 0.50
MAPT P10636 1/20 0.50
MPI P34949 1/20 0.50
CDC25B P30305 3/20 0.42
TRPM4 Q8TD43 1/20 0.39
SIGMAR1 Q99720 5/20 0.38
CYP1A2 P05177 3/20 0.38
HSD17B10 Q99714 2/20 0.37
GLA P06280 1/20 0.37
CYP2C19 P33261 1/20 0.37
APAF1 O14727 1/20 0.36
CASP3 P42574 1/20 0.36
CASP6 P55212 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24153839 0.81 ALDH1A1 (0.39) NQO2ALDH1A1KDM4EMEN1HPGD
SCHEMBL9888888 0.79 TRPM4 (0.43) ALDH1A1KDM4EMEN1HPGDKMT2A
SCHEMBL4369691 0.78 CYP1A2 (0.52) ALDH1A1KDM4EMEN1HPGDKMT2A
SCHEMBL22760563 0.77 SIGMAR1 (0.45) ALDH1A1KDM4EMEN1KMT2AMAPT
SCHEMBL14975317 0.77 NQO2 (0.55) NQO2ALDH1A1KDM4EMEN1HPGD
SCHEMBL14069628 0.77 TRPM4 (0.42) ALDH1A1KDM4EMEN1HPGDKMT2A
SCHEMBL16125391 0.76 SIGMAR1 (0.47) SIGMAR1CYP1A2CYP2C19
SCHEMBL1408788 0.76 NQO2 (0.50) NQO2ALDH1A1KDM4EMEN1HPGD
SCHEMBL15730661 0.76 ALDH1A1 (0.42) ALDH1A1KDM4EMEN1HPGDKMT2A
SCHEMBL13720442 0.76 ALDH1A1 (0.42) ALDH1A1KDM4EMEN1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11637249-B2 Organic electroluminescent element KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-04-25 US disclosed
US-11539003-B2 Polycyclic aromatic amino compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-12-27 US disclosed
US-11539003-B2 Polycyclic aromatic amino compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-12-27 US disclosed
CN-110049990-B Polycyclic aromatic amino compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2022-09-13 CN disclosed
CN-112236435-A Polycyclic aromatic compound and multimer thereof 学校法人关西学院 2021-01-15 CN disclosed
US-20200176680-A1 ORGANIC ELECTROLUMINESCENT ELEMENT KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2020-06-04 US disclosed
US-20200176680-A1 ORGANIC ELECTROLUMINESCENT ELEMENT KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2020-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11539003-B2 Polycyclic aromatic amino compound BCAT2, BCAT1, SLC7A5 NQO2 4070/4885ALDH1A1 3738/4885KDM4E 672/4885
US-11637249-B2 Organic electroluminescent element BMI1, TCF4, LEF1 NQO2 3314/4885ALDH1A1 219/4885KDM4E 929/4885
US-20200176680-A1 ORGANIC ELECTROLUMINESCENT ELEMENT BMI1, TCF4, LEF1 NQO2 3314/4885ALDH1A1 219/4885KDM4E 929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.