SCHEMBL21993463

SCHEMBL21993463

COCCCSc1ccc(O)cc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.50
LMNA P02545 1/20 0.47
CTDSP1 Q9GZU7 1/20 0.47
ALDH1A1 P00352 3/20 0.46
PKM P14618 2/20 0.46
HTT P42858 1/20 0.42
HSD17B10 Q99714 1/20 0.42
HSP90AA1 P07900 1/20 0.40
KCNH2 Q12809 1/20 0.40
CA2 P00918 1/20 0.40
NR1H2 P55055 1/20 0.39
SLC2A1 P11166 1/20 0.38
GAA P10253 1/20 0.37
MTNR1A P48039 1/20 0.37
MTNR1B P49286 1/20 0.37
RYR2 Q92736 2/20 0.36
CALM1 P0DP23 1/20 0.36
LTA4H P09960 1/20 0.36
NR5A1 Q13285 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26246267 0.92 KDM4E (0.51) KDM4ELMNACTDSP1ALDH1A1PKM
SCHEMBL6362994 0.88 LMNA (0.42) KDM4ELMNACTDSP1ALDH1A1PKM
SCHEMBL537146 0.83 LMNA (0.56) KDM4ELMNACTDSP1ALDH1A1HSD17B10
SCHEMBL536376 0.83 LMNA (0.51) KDM4ELMNACTDSP1ALDH1A1HSD17B10
SCHEMBL10698165 0.81 LMNA (0.54) KDM4ELMNACTDSP1ALDH1A1HSD17B10
SCHEMBL10699634 0.81 LMNA (0.54) KDM4ELMNACTDSP1ALDH1A1HSD17B10
SCHEMBL2940920 0.80 KDM4E (0.50) KDM4EALDH1A1PKMHTTHSD17B10
SCHEMBL389159 0.79 KDM4E (0.46) KDM4EALDH1A1PKMHTTHSD17B10
SCHEMBL4399477 0.79 MAOA (0.53) KDM4ELMNACTDSP1ALDH1A1HSD17B10
SCHEMBL642392 0.79 ALDH1A1 (0.58) KDM4ELMNAALDH1A1PKMMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702578-B2 Thermally conductive material, device with thermally conductive layer, composition for forming thermally conductive material, and disk-like liquid crystal compound FUJIFILM CORPORATION (JP) 2023-07-18 US disclosed
US-11702578-B2 Thermally conductive material, device with thermally conductive layer, composition for forming thermally conductive material, and disk-like liquid crystal compound FUJIFILM CORPORATION (JP) 2023-07-18 US disclosed
US-20200148931-A1 THERMALLY CONDUCTIVE MATERIAL, DEVICE WITH THERMALLY CONDUCTIVE LAYER, COMPOSITION FOR FORMING THERMALLY CONDUCTIVE MATERIAL, AND DISK-LIKE LIQUID CRYSTAL COMPOUND FUJIFILM CORPORATION (JP) 2020-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200148931-A1 THERMALLY CONDUCTIVE MATERIAL, DEVICE WITH THERMALLY CONDUCTIVE LAYER, COMPOSITION FOR FORMING THERMALLY CONDUCTIVE MATERIAL, AND DISK-LIKE LIQUID CRYSTAL COMPOUND PYCARD, ASIC3, CRYAA KDM4E 702/4885LMNA 1889/4885CTDSP1 3263/4885
US-11702578-B2 Thermally conductive material, device with thermally conductive layer, composition for forming thermally conductive material, and disk-like liquid crystal compound PYCARD, ASIC3, CRYAA KDM4E 702/4885LMNA 1889/4885CTDSP1 3263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.