SCHEMBL22000751

SCHEMBL22000751

CCCC(C)(C)N(C(C)=O)C(C)(C)CCC

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
LMNA P02545 2/20 0.34
HSD17B10 Q99714 1/20 0.34
CES2 O00748 1/20 0.31
FDPS P14324 2/20 0.31
TDP1 Q9NUW8 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9400179 0.79 CHRM2 (0.33) ALDH1A1TDP1
SCHEMBL23252699 0.78 FDPS (0.34) ALDH1A1LMNAHSD17B10FDPS
SCHEMBL19458601 0.78 LMNA (0.42) ALDH1A1LMNAHSD17B10FDPSTDP1
SCHEMBL23663504 0.73 ALDH1A1 (0.38) ALDH1A1LMNAHSD17B10
SCHEMBL17710552 0.72
SCHEMBL12326370 0.70 ALDH1A1 (0.34) ALDH1A1LMNAHSD17B10FDPSTDP1
SCHEMBL9930151 0.67 FDPS (0.31) ALDH1A1LMNAHSD17B10FDPS
SCHEMBL6544006 0.67
SCHEMBL22081708 0.67 LMNA (0.41) ALDH1A1LMNAHSD17B10FDPSTDP1
SCHEMBL14479855 0.67 ALDH1A1 (0.32) ALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11214578-B2 Urea/carbamates FAAH MAGL or dual FAAH/MAGL inhibitors and uses thereof NORTHEASTERN UNIVERSITY (US) 2022-01-04 US disclosed
US-20200148696-A1 Urea/Carbamates FAAH MAGL Or Dual FAAH/MAGL Inhibitors And Uses Thereof NORTHEASTERN UNIVERSITY 2020-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11214578-B2 Urea/carbamates FAAH MAGL or dual FAAH/MAGL inhibitors and uses thereof FAAH, FAAH2, MGLL ALDH1A1 687/4885LMNA 2835/4885HSD17B10 907/4885
US-20200148696-A1 Urea/Carbamates FAAH MAGL Or Dual FAAH/MAGL Inhibitors And Uses Thereof FAAH, MGLL, FAAH2 ALDH1A1 2074/4885LMNA 2315/4885HSD17B10 1734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.