Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3287403 | 0.87 | DNM1 (0.51) | CYP1A2CYP2D6GAACYP3A4DNM1 | |
| SCHEMBL24225247 | 0.83 | ALDH1A1 (0.46) | ALDH1A1GAAHPGDDNM1LMNA | |
| SCHEMBL13407923 | 0.81 | SMN1; SMN2 (0.46) | ALDH1A1CYP1A2CYP2D6GAACYP3A4 | |
| SCHEMBL15468358 | 0.81 | CASP2 (0.53) | ALDH1A1CYP1A2CYP2D6GAACYP3A4 | |
| SCHEMBL11441214 | 0.81 | CASP2 (0.46) | ALDH1A1HPGDDNM1LMNAKMT2A | |
| SCHEMBL14548967 | 0.80 | ALDH1A1 (0.43) | ALDH1A1GAAKDM4EHPGDDNM1 | |
| SCHEMBL20622920 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HPGDDNM1LMNAACHE | |
| SCHEMBL24626058 | 0.79 | CYP1A2 (0.46) | ALDH1A1CYP1A2CYP2D6GAACYP3A4 | |
| SCHEMBL3288269 | 0.79 | DNM1 (0.53) | ALDH1A1GAADNM1LMNACNR1 | |
| SCHEMBL1518045 | 0.79 | ALDH1A1 (0.57) | ALDH1A1GAAHPGDDNM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200155692-A1 | DENDRIMER DRUG CONJUGATES FOR SUSTAINED INTRA-ARTICULAR DELIVERY | UNITED STATES GOVERNMENT | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200155692-A1 | DENDRIMER DRUG CONJUGATES FOR SUSTAINED INTRA-ARTICULAR DELIVERY | CD44, ITGA6, ITGA2B | ALDH1A1 980/4885CYP1A2 4329/4885CYP2D6 1673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.