SCHEMBL3287403

SCHEMBL3287403

CCN(CC)CCNC(=O)CCCCCCCCCCCCCCC(C)C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.51
FAAH O00519 4/20 0.46
KDM4C Q9H3R0 2/20 0.45
KDM4A O75164 1/20 0.45
PHF8 Q9UPP1 1/20 0.45
KDM2A Q9Y2K7 1/20 0.45
HDAC3 O15379 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC10 Q969S8 1/20 0.45
HDAC11 Q96DB2 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
HDAC9 Q9UKV0 1/20 0.45
HDAC5 Q9UQL6 1/20 0.45
PAOX Q6QHF9 1/20 0.43
CNR1 P21554 2/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3288269 0.92 DNM1 (0.53) DNM1FAAHKDM4CKDM4APHF8
SCHEMBL22003254 0.87 ALDH1A1 (0.48) DNM1CNR1GAALMNAPKM
SCHEMBL3288351 0.84 DNM1 (0.68) DNM1FAAHKDM4CKDM4APHF8
SCHEMBL6704069 0.84 FAAH (0.61) DNM1FAAHL3MBTL1SIRT2
SCHEMBL3005968 0.83 DNM1 (0.72) DNM1FAAHHDAC3HDAC4HDAC1
SCHEMBL74996 0.83 DNM1 (0.72) DNM1FAAHHDAC3HDAC4HDAC1
SCHEMBL6729860 0.83 DNM1 (0.72) DNM1FAAHHDAC3HDAC4HDAC1
SCHEMBL8398925 0.83 DNM1 (0.72) DNM1FAAHHDAC3HDAC4HDAC1
SCHEMBL76373 0.83 DNM1 (0.72) DNM1FAAHHDAC3HDAC4HDAC1
SCHEMBL74483 0.83 DNM1 (0.72) DNM1FAAHHDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1894556-B2 Aqueous hair cosmetic composition KAO CORP (JP) 2016-08-10 EP disclosed
EP-2682096-B1 COSMETIC BASE MATERIAL, AND COSMETIC CONTAINING SAID COSMETIC BASE MATERIAL SEIWA KASEI CO LTD (JP) 2015-12-30 EP disclosed
EP-2682096-A1 COSMETIC BASE MATERIAL, AND COSMETIC CONTAINING SAID COSMETIC BASE MATERIAL Seiwa Kasei Company, Limited (JP) 2014-01-08 EP disclosed
EP-1894556-B1 Aqueous hair cosmetic composition KAO CORP (JP) 2013-04-17 EP disclosed
EP-2535039-A1 COSMETIC BASE MATERIAL, AND COSMETIC CONTAINING SAID COSMETIC BASE MATERIAL Seiwa Kasei Company, Limited (JP) 2012-12-19 EP disclosed
CN-102834088-A Cosmetic base material, and cosmetic containing said cosmetic base material SEIWA KASEI CO LTD 2012-12-19 CN disclosed
US-20120288463-A1 COSMETIC BASE MATERIAL AND COSMETIC CONTAINING THIS COSMETIC BASE MATERIAL SEIWA KASEI CO., LTD. (JP) 2012-11-15 US disclosed
US-7718816-B2 Carboxamide derivative, processes for producing the same, and detergent composition LION AKZO CO., LTD. (JP) 2010-05-18 US disclosed
US-7585989-B2 Production process for carboxylic amide and derivatives thereof LION AKZO CO., LTD. (JP) 2009-09-08 US disclosed
EP-1894556-A2 Aqueous hair cosmetic composition Kao Corporation (JP) 2008-03-05 EP disclosed
US-20080050330-A1 AQUEOUS HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2008-02-28 US disclosed
US-20070060762-A1 Production process for carboxylic amide and derivatives thereof LION AKZO CO., LTD. (JP) 2007-03-15 US disclosed
US-20070010680-A1 Carboxamide derivative, processes for producing the same, and detergent composition LION AKZO CO., LTD. (JP) 2007-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120288463-A1 COSMETIC BASE MATERIAL AND COSMETIC CONTAINING THIS COSMETIC BASE MATERIAL SSB, LNPEP, CUTA DNM1 1854/4885FAAH 683/4885KDM4C 4728/4885
US-20070010680-A1 Carboxamide derivative, processes for producing the same, and detergent composition FAAH2, FAAH, NAAA DNM1 978/4885FAAH 2/4885KDM4C 1696/4885
US-20080050330-A1 AQUEOUS HAIR COSMETIC COMPOSITION SHH, POLR1C, CUTA DNM1 3800/4885FAAH 1063/4885KDM4C 2540/4885
US-20070060762-A1 Production process for carboxylic amide and derivatives thereof COASY, BCAT2, ODC1 DNM1 2054/4885FAAH 591/4885KDM4C 2921/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.