SCHEMBL22004244

SCHEMBL22004244

CCOC(=O)C(CC(=O)C12CC3CC(CC(C3)C1)C2)(OCCC(F)(F)C(F)(F)S(=O)(=O)O)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
EPHX2 P34913 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
ALDH1A1 P00352 3/20 0.32
TSHR P16473 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
MAPT P10636 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22004245 0.91 HSD11B1 (0.33) ALDH1A1NPSR1
SCHEMBL13464729 0.82 LMNA (0.33) LMNAEPHX2CYP3A4CYP2D6CYP2C9
SCHEMBL21754744 0.81 LMNA (0.36) LMNAEPHX2CYP3A4CYP2D6CYP2C9
SCHEMBL19387776 0.79 ALDH1A1 (0.34) EPHX2ALDH1A1MAPT
SCHEMBL15186548 0.78 EPHX2 (0.31) EPHX2
SCHEMBL22759048 0.78 EPHX2 (0.31) EPHX2
SCHEMBL17066105 0.77 HSD11B1 (0.36) LMNAALDH1A1TSHRNPSR1
SCHEMBL15183217 0.77 LMNA (0.32) LMNAEPHX2ALDH1A1
SCHEMBL15655907 0.76 HSD11B1 (0.38) LMNAALDH1A1TSHR
SCHEMBL15183242 0.76 LMNA (0.32) LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11385542-B2 Salt, quencher, resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-07-12 US disclosed
US-20200159116-A1 SALT, QUENCHER, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200159116-A1 SALT, QUENCHER, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SLC11A2, MSR1, NHERF1 LMNA 3801/4885EPHX2 2797/4885CYP3A4 879/4885
US-11385542-B2 Salt, quencher, resist composition and method for producing resist pattern SLC11A2, MSR1, NHERF1 LMNA 3801/4885EPHX2 2797/4885CYP3A4 879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.