SCHEMBL22004245

SCHEMBL22004245

CCOC(=O)C(CC(=O)C12CC3CC(CC(O)(C3)C1)C2)(OCCC(F)(F)C(F)(F)S(=O)(=O)O)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.33
ALDH1A1 P00352 2/20 0.32
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GAA P10253 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22004244 0.91 LMNA (0.35) ALDH1A1NPSR1
SCHEMBL23975665 0.84 ALDH1A1 (0.35) HSD11B1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL13464644 0.84 ALDH1A1 (0.35) HSD11B1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL24186261 0.83 ALDH1A1 (0.35) HSD11B1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL22446104 0.79 SCN9A (0.33)
SCHEMBL20110634 0.78 HSD11B1 (0.40) HSD11B1ALDH1A1NPC1RAB9AGAA
SCHEMBL8898768 0.78 ALDH1A1 (0.46) HSD11B1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL22958152 0.78 DPP4 (0.31)
SCHEMBL14760457 0.77 ALDH1A1 (0.46) HSD11B1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL16843428 0.77 HSD11B1 (0.38) HSD11B1ALDH1A1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11385542-B2 Salt, quencher, resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-07-12 US disclosed
US-20200159116-A1 SALT, QUENCHER, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200159116-A1 SALT, QUENCHER, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SLC11A2, MSR1, NHERF1 HSD11B1 244/4885ALDH1A1 3027/4885NPC1 1600/4885
US-11385542-B2 Salt, quencher, resist composition and method for producing resist pattern SLC11A2, MSR1, NHERF1 HSD11B1 244/4885ALDH1A1 3027/4885NPC1 1600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.