SCHEMBL2200629

SCHEMBL2200629

COc1cccc(C(c2cc(C)c(O)c(C)c2)c2cc(C)c(O)c(C)c2)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.47
KDM4E B2RXH2 3/20 0.47
HPGD P15428 2/20 0.47
ALOX15 P16050 2/20 0.47
HSD17B10 Q99714 2/20 0.47
ALDH1A1 P00352 2/20 0.47
LMNA P02545 1/20 0.47
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
ALOX12 P18054 1/20 0.47
MAPK1 P28482 1/20 0.47
CYP1A2 P05177 1/20 0.45
ALOX5 P09917 1/20 0.44
PTGS1 P23219 1/20 0.44
PTGS2 P35354 1/20 0.44
CYP2C19 P33261 2/20 0.43
CYP2D6 P10635 1/20 0.43
BCHE P06276 1/20 0.42
TYR P14679 1/20 0.42
ACHE P22303 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29908290 1.00 MAPT (0.47) MAPTKDM4EHPGDALOX15HSD17B10
SCHEMBL20808568 0.81 ALOX5 (0.39) MAPTCYP3A4ALOX5PTGS1PTGS2
SCHEMBL2860977 0.80 TRPA1 (0.47) MAPTKDM4EHPGDALOX15HSD17B10
SCHEMBL7448667 0.79 MAPT (0.57) MAPTKDM4EHPGDALOX15HSD17B10
SCHEMBL8151507 0.79 PTGS1 (0.44) HPGDALDH1A1LMNACYP3A4CYP1A2
SCHEMBL30375446 0.78 MAPT (0.49) MAPTKDM4EHPGDALOX15HSD17B10
SCHEMBL278351 0.78 MAPT (0.49) MAPTKDM4EHPGDALOX15HSD17B10
SCHEMBL31409236 0.77 MAPT (0.47) MAPTKDM4EHPGDALOX15HSD17B10
SCHEMBL2200950 0.77 CYP1A2 (0.48) MAPTKDM4EHPGDALOX15HSD17B10
SCHEMBL2200512 0.76 CYP1A2 (0.47) MAPTKDM4EHPGDALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7662904-B2 polyethersulfone copolymers; thermal stability, chemical resistance and mechanical strength due to their structural and crosslinked characteristics; uniform thickness when they are used for optical films, sheets, and display; electrooptic devices KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2010-02-16 US claimed
US-20060217518-A1 Aromatic polyether resins crosslinked by amic acid or imide side chain KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY 2006-09-28 US claimed
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT THE PILOT INK CO., LTD. (JP) 2026-03-05 US disclosed
EP-3954745-B1 REVERSIBLY THERMOCHROMIC AQUEOUS INK COMPOSITION FOR WRITING UTENSILS, AND REFILL AND WATER-BASED BALLPOINT PEN EACH INTERNALLY CONTAINING SAME KK PILOT CORPORATION ALSO TRADING AS PILOT CORPORATION (JP) 2026-01-07 EP disclosed
US-12460099-B2 Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment THE PILOT INK CO., LTD. (JP) 2025-11-04 US disclosed
US-12421411-B2 Aqueous ink composition for reversibly thermochromic writing instrument, and refill and aqueous ballpoint pen incorporating aqueous ink composition for reversibly thermochromic writing instrument KABUSHIKI KAISHA PILOT CORPORATION (JP) 2025-09-23 US disclosed
US-12421349-B2 Polyphenylene ether composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-09-23 US disclosed
EP-4306571-B1 POLYPHENYLENE ETHER, METHOD FOR PRODUCING SAME, THERMALLY CURABLE COMPOSITION, PREPREG, AND MULTILAYER BODY ASAHI CHEMICAL IND (JP) 2024-12-25 EP disclosed
US-20240166812-A1 POLYPHENYLENE ETHER, PRODUCTION METHOD OF THE SAME, THERMOSETTING COMPOSITION, PREPREG, AND LAMINATE ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-05-23 US disclosed
EP-4306571-A1 POLYPHENYLENE ETHER, METHOD FOR PRODUCING SAME, THERMALLY CURABLE COMPOSITION, PREPREG, AND MULTILAYER BODY Asahi Kasei Kabushiki Kaisha (JP) 2024-01-17 EP disclosed
EP-4039728-B1 POLYPHENYLENE ETHER COMPOSITION ASAHI CHEMICAL IND (JP) 2023-10-11 EP disclosed
US-20060217518-A1 Aromatic polyether resins crosslinked by amic acid or imide side chain KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY 2006-09-28 US disclosed
US-20060159839-A1 Photosensitive resin composition, electronic component using the same, and display using same TORAY INDUSTRIES, INC. (JP) 2006-07-20 US disclosed
US-20060110680-A1 Photosensitive resin composition TORAY INDUSTRIES, INC. (JP) 2006-05-25 US disclosed
EP-1630605-A1 PHOTOSENSITIVE RESIN COMPOSITION, AND ELECTRONIC COMPONENT AND DISPLAY USING SAME TORAY INDUSTRIES, INC. (JP) 2006-03-01 EP disclosed
US-6929890-B2 Positive-type photosensitive resin composition TORAY INDUSTRIES, INC. (JP) 2005-08-16 US disclosed
US-20050014876-A1 Photosensitive resin precursor composition TORAY INDUSTRIES, INC. (JP) 2005-01-20 US disclosed
EP-1496395-A2 Photosensitive resin precursor composition TORAY INDUSTRIES, INC. (JP) 2005-01-12 EP disclosed
EP-1475665-A1 Positive-type photosensitive resin composition TORAY INDUSTRIES, INC. (JP) 2004-11-10 EP disclosed
US-20040197703-A1 Positive-type photosensitive resin composition TORAY INDUSTRIES, INC. (JP) 2004-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT TYR, SCO2, HBB MAPT 1195/4885KDM4E 3963/4885HPGD 3663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.