SCHEMBL22011813

SCHEMBL22011813

CCCCCc1ccc(-c2cc3oc4cc(OCC)c(F)c(F)c4c3c(F)c2F)cn1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.35
MAPT P10636 2/20 0.33
RAB9A P51151 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALOX5 P09917 14/20 0.33
THRB P10828 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22010955 0.84 RARB (0.40) S1PR1MAPTRAB9AL3MBTL1
SCHEMBL22010835 0.83 RARB (0.40) MAPTRAB9AL3MBTL1
SCHEMBL22011104 0.81 NAAA (0.33) MAPTRAB9AL3MBTL1ALOX5THRB
SCHEMBL22010998 0.80 RARB (0.44) S1PR1MAPTRAB9AL3MBTL1
SCHEMBL22011802 0.77 CTSL (0.38) MAPTALOX5THRBBLM
SCHEMBL22010820 0.76 RARB (0.40) S1PR1
SCHEMBL22010811 0.76 KDM4E (0.36) MAPTALOX5
SCHEMBL22010968 0.76 PGAM1 (0.42) S1PR1L3MBTL1
SCHEMBL22011189 0.76 RARB (0.37) S1PR1MAPTRAB9AL3MBTL1
SCHEMBL22011788 0.74 PGAM1 (0.42) MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device YBX1, ZKSCAN2, RCC1 S1PR1 1710/4885MAPT 1234/4885RAB9A 2387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.