Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | CASP1 | P29466 | 3/20 | 0.48 |
| ▸ | CASP7 | P55210 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TYMS | P04818 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23824812 | 0.82 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TSHRKDM4E | |
| SCHEMBL24589026 | 0.78 | — | — | |
| SCHEMBL19257407 | 0.77 | CDK4 (0.36) | ALDH1A1HSD17B10MAPK1TSHRATM | |
| SCHEMBL24117185 | 0.76 | ALDH1A1 (0.34) | ALDH1A1HSD17B10MAPK1TSHRATM | |
| SCHEMBL2209672 | 0.75 | NPC1 (0.38) | ALDH1A1TSHRHPGDCYP3A4CYP1A2 | |
| SCHEMBL19257496 | 0.75 | CDK4 (0.38) | PARP1 | |
| SCHEMBL25006606 | 0.74 | ALDH1A1 (0.35) | ALDH1A1HSD17B10TSHRL3MBTL1HPGD | |
| SCHEMBL10014625 | 0.74 | IMPDH2 (0.45) | ALDH1A1HSD17B10ATMHPGDBCHE | |
| SCHEMBL14951394 | 0.73 | MAPK1 (0.41) | ALDH1A1HSD17B10MAPK1L3MBTL1HPGD | |
| SCHEMBL18529231 | 0.73 | CYP2A6 (0.39) | ALDH1A1HSD17B10MAPK1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12035625-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2024-07-09 | — | — | US | disclosed |
| US-12035625-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2024-07-09 | — | — | US | disclosed |
| CN-113195500-B | Material for organic electroluminescent device | 默克专利有限公司 | 2024-05-17 | — | — | CN | disclosed |
| EP-3880682-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-06-14 | — | — | EP | disclosed |
| EP-3880682-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-06-14 | — | — | EP | disclosed |
| US-20220223801-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-07-14 | — | — | US | disclosed |
| US-20220006030-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-01-06 | — | — | US | disclosed |
| WO-2020099307-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220223801-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | TMEM109, PIEZO1, L1CAM | ALDH1A1 8/4885HSD17B10 1776/4885MAPK1 60/4885 |
| US-20220006030-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | ZYX, RER1, AOC2 | ALDH1A1 1119/4885HSD17B10 4135/4885MAPK1 560/4885 |
| US-12035625-B2 | Materials for organic electroluminescent devices | ZYX, RER1, AOC2 | ALDH1A1 1119/4885HSD17B10 4135/4885MAPK1 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.