Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGAM1 | P18669 | 2/20 | 0.45 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28779648 | 0.95 | PGAM1 (0.45) | PGAM1NR5A1GPR84ALOX5LTA4H | |
| SCHEMBL29742157 | 0.95 | PGAM1 (0.45) | PGAM1NR5A1GPR84ALOX5LTA4H | |
| SCHEMBL28877162 | 0.80 | ALOX5 (0.49) | PGAM1NR5A1GPR84ALOX5LTA4H | |
| SCHEMBL25797619 | 0.78 | THRA (0.54) | NR5A1ALOX5LTA4HTHRATHRB | |
| SCHEMBL9641086 | 0.78 | THRA (0.54) | NR5A1ALOX5LTA4HTHRATHRB | |
| SCHEMBL25797639 | 0.75 | NR5A1 (0.54) | NR5A1GPR84LTA4H | |
| SCHEMBL8067639 | 0.74 | L3MBTL1 (0.42) | LTA4HTHRATHRB | |
| SCHEMBL18487563 | 0.74 | LTA4H (0.49) | NR5A1ALOX5LTA4HTHRATHRB | |
| SCHEMBL29742352 | 0.74 | GLA (0.39) | THRATHRB | |
| SCHEMBL20819709 | 0.74 | CCNB2 (0.38) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662378-B2 | Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2020-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662378-B2 | Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device | YBX1, ZKSCAN2, RCC1 | PGAM1 4829/4885NR5A1 3224/4885GPR84 3493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.