SCHEMBL22011818

SCHEMBL22011818

CCCCCc1ccc(-c2ccc(-c3cc4oc5cc(OCCC)c(F)c(F)c5c4c(F)c3F)c(F)c2)cc1F

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.35
MAOA P21397 2/20 0.34
RARB P10826 4/20 0.31
PPARD Q03181 1/20 0.31
NAAA Q02083 1/20 0.31
ABCB1 P08183 1/20 0.31
RARA P10276 2/20 0.31
RARG P13631 1/20 0.31
PGAM1 P18669 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22011104 0.86 NAAA (0.33) MAOBRARBNAAARARARARG
SCHEMBL22011002 0.85 L3MBTL1 (0.38) NAAA
SCHEMBL22011802 0.81 CTSL (0.38)
SCHEMBL22011189 0.79 RARB (0.37) RARBRARARARG
SCHEMBL22011181 0.78 PGAM1 (0.42) MAOBMAOAABCB1PGAM1
SCHEMBL10301559 0.76 CNR2 (0.41) RARBRARARARG
SCHEMBL22010998 0.76 RARB (0.44) RARBABCB1RARARARG
SCHEMBL22010820 0.76 RARB (0.40) RARBABCB1PGAM1
SCHEMBL22011081 0.75 MAOB (0.36) MAOBMAOAABCB1
SCHEMBL424417 0.74 NAAA (0.40) RARBNAAARARARARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device YBX1, ZKSCAN2, RCC1 MAOB 787/4885MAOA 1418/4885RARB 2226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.