Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22012076 | 0.79 | ASIC3 (0.37) | PRMT5WDR77 | |
| SCHEMBL22012078 | 0.78 | ASIC3 (0.34) | PRMT5WDR77 | |
| SCHEMBL21962438 | 0.73 | PRMT5 (0.32) | PRMT5WDR77 | |
| SCHEMBL22012770 | 0.73 | PRMT5 (0.37) | PRMT5WDR77 | |
| SCHEMBL30244373 | 0.72 | NLRP3 (0.39) | PRMT5WDR77 | |
| SCHEMBL22012981 | 0.72 | NLRP3 (0.39) | PRMT5WDR77 | |
| SCHEMBL30244016 | 0.72 | NLRP3 (0.39) | PRMT5WDR77 | |
| SCHEMBL22012077 | 0.72 | PRMT5 (0.34) | PRMT5WDR77 | |
| SCHEMBL22012071 | 0.70 | PNMT (0.38) | PRMT5WDR77 | |
| SCHEMBL25796678 | 0.64 | PARP1 (0.42) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102576-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |