Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 19/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 19/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22012076 | 0.87 | ASIC3 (0.37) | ASIC3PRMT5WDR77 | |
| SCHEMBL21962438 | 0.85 | PRMT5 (0.32) | ASIC3PRMT5WDR77 | |
| SCHEMBL22012769 | 0.78 | PRMT5 (0.36) | PRMT5WDR77 | |
| SCHEMBL30244373 | 0.75 | NLRP3 (0.39) | PRMT5WDR77 | |
| SCHEMBL30244016 | 0.75 | NLRP3 (0.39) | PRMT5WDR77 | |
| SCHEMBL22012981 | 0.75 | NLRP3 (0.39) | PRMT5WDR77 | |
| SCHEMBL22012077 | 0.75 | PRMT5 (0.34) | PRMT5WDR77 | |
| SCHEMBL22012071 | 0.74 | PNMT (0.38) | ASIC3PRMT5WDR77 | |
| SCHEMBL22012770 | 0.69 | PRMT5 (0.37) | ASIC3PRMT5WDR77 | |
| SCHEMBL25796836 | 0.68 | CA2 (0.35) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102576-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |