Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27358210 | 0.93 | GABRA1 (0.48) | GABRA1GABRB2 | |
| SCHEMBL548187 | 0.85 | GABRA1 (0.45) | GABRA1GABRB2 | |
| SCHEMBL3969052 | 0.77 | GABRA1 (0.60) | GABRA1GABRB2 | |
| SCHEMBL4985878 | 0.77 | GABRA1 (0.52) | GABRA1GABRB2 | |
| SCHEMBL8985984 | 0.77 | MEN1 (0.42) | GABRA1GABRB2 | |
| SCHEMBL18802839 | 0.77 | ALOX15 (0.46) | GABRA1GABRB2 | |
| SCHEMBL7764602 | 0.77 | GABRA1 (0.60) | GABRA1GABRB2 | |
| SCHEMBL547694 | 0.77 | RXRB (0.40) | GABRA1GABRB2 | |
| SCHEMBL629909 | 0.75 | ESR1 (0.38) | — | |
| SCHEMBL548086 | 0.74 | GABRA1 (0.65) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102576-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |