Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.60 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 5/20 | 0.40 |
| ▸ | RXRA | P19793 | 4/20 | 0.40 |
| ▸ | RXRG | P48443 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764602 | 1.00 | GABRA1 (0.60) | GABRA1GABRB2POLBRXRBRXRA | |
| SCHEMBL548187 | 0.90 | GABRA1 (0.45) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL15726901 | 0.89 | GABRA1 (0.50) | GABRA1GABRB2POLBRXRBRXRA | |
| SCHEMBL23113536 | 0.87 | GABRA1 (0.48) | GABRA1GABRB2POLBRXRBRXRA | |
| SCHEMBL20933032 | 0.87 | GABRA1 (0.48) | GABRA1GABRB2POLBRXRBRXRA | |
| SCHEMBL27358210 | 0.87 | GABRA1 (0.48) | GABRA1GABRB2POLBRXRBRXRA | |
| SCHEMBL18077869 | 0.87 | GABRA1 (0.48) | GABRA1GABRB2POLBRXRBRXRA | |
| SCHEMBL13278178 | 0.87 | GABRA1 (0.48) | GABRA1GABRB2POLBRXRBRXRA | |
| SCHEMBL16259555 | 0.83 | GABRA1 (0.44) | GABRA1GABRB2POLBRXRBRXRA | |
| SCHEMBL15132423 | 0.83 | GABRA1 (0.44) | GABRA1GABRB2POLBRXRBRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013112585-A1 | SYNTHETIC METHODS PERTAINING TO TERT-BUTYL-BENZENE-BASED COMPOUNDS | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2013-08-01 | — | — | WO | claimed |
| US-20130190525-A1 | SYNTHETIC METHODS PERTAINING TO TERT-BUTYL-BENZENE-BASED COMPOUNDS | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2013-07-25 | — | — | US | claimed |
| EP-1553072-B1 | METHOD FOR PRODUCING CHLORINATED HYDROCARBON HAVING CHLORINATED TERTIARY CARBON | KANEKA CORP (JP) | 2009-03-11 | — | — | EP | claimed |
| US-7304192-B2 | Method for producing chlorinated hydrocarbon having chlorinated tertiary carbon | KANEKA CORPORATION (JP) | 2007-12-04 | — | — | US | claimed |
| US-9874816-B2 | Radiation-sensitive resin composition and resist pattern-forming method | JSR CORPORATION (JP) | 2018-01-23 | — | — | US | disclosed |
| US-20170363961-A9 | RADIATION-SENSITIVE RESIN COMPOSITION AND RESIST PATTERN-FORMING METHOD | JSR CORPORATION (JP) | 2017-12-21 | — | — | US | disclosed |
| US-20160202608-A1 | RADIATION-SENSITIVE RESIN COMPOSITION AND RESIST PATTERN-FORMING METHOD | JSR CORPORATION (JP) | 2016-07-14 | — | — | US | disclosed |
| US-8889926-B2 | Method for the synthesis of low cost initiators for telechelic polyisobutylenes | THE UNIVERSITY OF AKRON (US) | 2014-11-18 | — | — | US | disclosed |
| US-8889926-B2 | Method for the synthesis of low cost initiators for telechelic polyisobutylenes | THE UNIVERSITY OF AKRON (US) | 2014-11-18 | — | — | US | disclosed |
| US-20140235905-A1 | METHOD FOR THE SYNTHESIS OF LOW COST INITIATORS FOR TELECHELIC POLYISOBUTYLENES | THE UNIVERSITY OF AKRON (US) | 2014-08-21 | — | — | US | disclosed |
| US-20140235905-A1 | METHOD FOR THE SYNTHESIS OF LOW COST INITIATORS FOR TELECHELIC POLYISOBUTYLENES | THE UNIVERSITY OF AKRON (US) | 2014-08-21 | — | — | US | disclosed |
| US-8697119-B2 | Medical devices and materials containing isobutylene copolymer | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2014-04-15 | — | — | US | disclosed |
| US-20110213084-A1 | POLYMERS HAVING BOTH HARD AND SOFT SEGMENTS, AND PROCESS FOR MAKING SAME | THE UNIVERSITY OF AKRON (US) | 2011-09-01 | — | — | US | disclosed |
| EP-1848769-A1 | MEDICAL DEVICES AND MATERIALS CONTAINING ISOBUTYLENE COPOLYMER | Boston Scientific Limited (BB) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006020274-A1 | MEDICAL DEVICES AND MATERIALS CONTAINING ISOBUTYLENE COPOLYMER | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2006-02-23 | — | — | WO | disclosed |
| US-20060013867-A1 | Medical devices and materials containing isobutylene copolymer | BOSTON SCIENTIFIC SCIMED, INC. | 2006-01-19 | — | — | US | disclosed |
| EP-1553072-A1 | METHOD FOR PRODUCING CHLORINATED HYDROCARBON HAVING CHLORINATED TERTIARY CARBON | KANEKA CORPORATION (JP) | 2005-07-13 | — | — | EP | disclosed |
| EP-0468041-A4 | HALOGEN TERMINATED POLY(HALOSTYRENES) AND A PROCESS FOR THE PREPARATION THEREOF | — | 1992-07-22 | — | — | EP | disclosed |
| EP-0468041-A1 | HALOGEN TERMINATED POLY(HALOSTYRENES) AND A PROCESS FOR THE PREPARATION THEREOF | The University of Akron (US) | 1992-01-29 | — | — | EP | disclosed |
| WO-1991012281-A1 | HALOGEN TERMINATED POLY(HALOSTYRENES) AND A PROCESS FOR THE PREPARATION THEREOF | THE UNIVERSITY OF AKRON (US) | 1991-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190525-A1 | SYNTHETIC METHODS PERTAINING TO TERT-BUTYL-BENZENE-BASED COMPOUNDS | TERT, HMBS, BET1 | GABRA1 598/4885GABRB2 415/4885POLB 36/4885 |
| US-20060013867-A1 | Medical devices and materials containing isobutylene copolymer | ABCB1, HMGB2, HMGB3 | GABRA1 931/4885GABRB2 489/4885POLB 252/4885 |
| US-20140235905-A1 | METHOD FOR THE SYNTHESIS OF LOW COST INITIATORS FOR TELECHELIC POLYISOBUTYLENES | TERT, TBCB, CAT | GABRA1 1456/4885GABRB2 606/4885POLB 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.