Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.48 |
| ▸ | NOS1 | P29475 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | GRM8 | O00222 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4797264 | 0.84 | ROCK2 (0.50) | NOS3NOS1MAPTHPGDRAB9A | |
| SCHEMBL27740085 | 0.82 | NOS3 (0.45) | NOS3NOS1MAPTHPGDRAB9A | |
| SCHEMBL29391506 | 0.80 | GRM8 (0.49) | NOS3NOS1MAPTHPGDRAB9A | |
| SCHEMBL16659380 | 0.80 | MAPT (0.52) | NOS3NOS1MAPTHPGDRAB9A | |
| SCHEMBL28999792 | 0.79 | LMNA (0.46) | NOS3NOS1MAPTHPGDRAB9A | |
| SCHEMBL50646 | 0.79 | MAPT (0.68) | NOS3NOS1MAPTHPGDRAB9A | |
| SCHEMBL26713389 | 0.79 | GRM8 (0.48) | NOS3NOS1MAPTHPGDRAB9A | |
| SCHEMBL527583 | 0.78 | MAPT (0.50) | NOS3NOS1MAPTHPGDRAB9A | |
| SCHEMBL9683939 | 0.78 | MAPT (0.50) | NOS3NOS1MAPTHPGDRAB9A | |
| SCHEMBL182327 | 0.78 | CYP2C9 (0.55) | NOS3NOS1MAPTHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099596-A1 | NOVEL PATHWAY FOR THE SYNTHESIS OF DIAZIRINES, THAT MAY OR MAY NOT BE ENRICHED IN NITROGEN-15 | UNIVERSITE DE ROUEN NORMANDIE (FR) | 2020-05-22 | — | — | WO | disclosed |