Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.69 |
| ▸ | NPC1 | O15118 | 4/20 | 0.69 |
| ▸ | RAB9A | P51151 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | PKM | P14618 | 2/20 | 0.69 |
| ▸ | P4HB | P07237 | 1/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.65 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10567185 | 1.00 | MAPT (0.69) | MAPTKDM4ENPC1RAB9ALMNA | |
| SCHEMBL10376888 | 0.83 | HSP90AA1 (0.55) | MAPTKDM4ENPC1RAB9ALMNA | |
| SCHEMBL10376889 | 0.83 | HSP90AA1 (0.55) | MAPTKDM4ENPC1RAB9ALMNA | |
| Pyrazinamide SCHEMBL28973464 | 0.82 | ADORA3 (0.60) | MAPTKDM4ENPC1RAB9ALMNA | |
| SCHEMBL977480 | 0.81 | MAPT (1.00) | MAPTKDM4ENPC1RAB9ALMNA | |
| SCHEMBL4400320 | 0.81 | MAPT (1.00) | MAPTKDM4ENPC1RAB9ALMNA | |
| SCHEMBL3595621 | 0.80 | BCHE (0.54) | MAPTKDM4ENPC1RAB9ALMNA | |
| SCHEMBL3595625 | 0.80 | BCHE (0.54) | MAPTKDM4ENPC1RAB9ALMNA | |
| SCHEMBL13381516 | 0.80 | KDM4E (0.78) | MAPTKDM4ENPC1RAB9ALMNA | |
| SCHEMBL979408 | 0.79 | CYP1B1 (1.00) | MAPTLMNACYP1B1CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12016312-B2 | Animal models, screening methods, and treatment methods for intraocular diseases or disorders | Smilebiotek Zhuhai Limited (CN) | 2024-06-25 | — | — | US | disclosed |
| US-12016312-B2 | Animal models, screening methods, and treatment methods for intraocular diseases or disorders | Smilebiotek Zhuhai Limited (CN) | 2024-06-25 | — | — | US | disclosed |
| US-20220015338-A1 | ANIMAL MODELS, SCREENING METHODS, AND TREATMENT METHODS FOR INTRAOCULAR DISEASES OR DISORDERS | Smilebiotek Zhuhai Limited (CN) | 2022-01-20 | — | — | US | disclosed |
| US-20220016146-A1 | METHOD OF TREATING AGE-RELATED MACULAR DEGENERATION | Smilebiotek Zhuhai Limited (CN) | 2022-01-20 | — | — | US | disclosed |
| WO-2020113373-A1 | METHOD OF TREATING AGE-RELATED MACULAR DEGENERATION | ZHUHAI QIWEI BIO-TECHNOLOGY LTD. (CN) | 2020-06-11 | — | — | WO | disclosed |
| WO-2020113759-A1 | METHOD OF TREATING AGE-RELATED MACULAR DEGENERATION | ZHUHAI QIWEI BIO-TECHNOLOGY LTD. (CN) | 2020-06-11 | — | — | WO | disclosed |
| WO-2020098630-A1 | ANIMAL MODELS, SCREENING METHODS, AND TREATMENT METHODS FOR INTRAOCULAR DISEASES OR DISORDERS | ZHUHAI QIWEI BIO-TECHNOLOGY LTD. (CN) | 2020-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220016146-A1 | METHOD OF TREATING AGE-RELATED MACULAR DEGENERATION | AGER, CASP3, PDE6D | MAPT 1668/4885KDM4E 4518/4885NPC1 1402/4885 |
| US-12016312-B2 | Animal models, screening methods, and treatment methods for intraocular diseases or disorders | MB, MYOC, PDE6A | MAPT 2250/4885KDM4E 4670/4885NPC1 782/4885 |
| US-20220015338-A1 | ANIMAL MODELS, SCREENING METHODS, AND TREATMENT METHODS FOR INTRAOCULAR DISEASES OR DISORDERS | MB, MYOC, PDE6A | MAPT 2250/4885KDM4E 4670/4885NPC1 782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.