Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | EGFR | P00533 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | WNT3A | P56704 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | BTK | Q06187 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | CCR5 | P51681 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22017772 | 0.84 | BRAF (0.64) | EGFR | |
| SCHEMBL12345537 | 0.83 | NPC1 (0.62) | KMT2ALMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13880941 | 0.82 | KMT2A (0.58) | KMT2AEGFRLMNAALDH1A1HPGD | |
| SCHEMBL2217357 | 0.81 | HDAC8 (0.64) | KMT2AALDH1A1HPGDSMN1; SMN2USP2 | |
| SCHEMBL2215952 | 0.80 | HDAC8 (0.63) | KMT2AALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL28668646 | 0.79 | PKM (0.79) | KMT2ALMNASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL15381993 | 0.79 | ALDH1A1 (0.64) | KMT2AEGFRLMNAALDH1A1HPGD | |
| SCHEMBL22017395 | 0.78 | EGFR (0.49) | EGFRSMN1; SMN2MAPTHSD17B10WNT3A | |
| SCHEMBL14845834 | 0.77 | BTK (0.67) | LMNAALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL21382964 | 0.77 | RAB9A (0.60) | EGFRLMNAALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020098710-A1 | SUBSTITUTED BIS-ARYL AMIDE COMPOUND AND PREPARATION METHOD AND APPLICATION THEREFOR | 中国医学科学院医药生物技术研究所 | 2020-05-22 | — | — | WO | disclosed |