Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.53 |
| ▸ | CES1 | P23141 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 5/20 | 0.52 |
| ▸ | CA2 | P00918 | 5/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.50 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22288 | 0.88 | CES2 (0.67) | CES2CES1CA1CA2HDAC1 | |
| Hydrochloric Acid SCHEMBL27781157 | 0.86 | CES2 (0.64) | CES2CES1CA1CA2HDAC1 | |
| SCHEMBL2263327 | 0.84 | TRPA1 (0.54) | MAPTALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL2202425 | 0.84 | TRPA1 (0.54) | MAPTALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL6667738 | 0.82 | CES2 (0.59) | CES2CES1CA1CA2MAPT | |
| SCHEMBL11511850 | 0.82 | PARP10 (0.66) | CES2CES1CA1CA2MAPT | |
| P-Anisic Acid SCHEMBL11874860 | 0.81 | CA1 (0.80) | CES2CES1CA1CA2MAPT | |
| SCHEMBL7722030 | 0.81 | HPGD (0.75) | CES2CES1CA1CA2MAPT | |
| SCHEMBL11763162 | 0.81 | ACHE (0.60) | CES2CES1CA1CA2MAPT | |
| SCHEMBL14130421 | 0.80 | PRSS1 (0.71) | CES2CES1CA1CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661309-B1 | Use of hydroperoxide derivatives of Cyclo-olefin copolymers | TICONA GMBH (DE) | 1998-11-25 | — | — | EP | disclosed |
| EP-0661309-A2 | Cyclo-olefin copolymers and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |