Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22027090 | 0.95 | NAAA (0.47) | SMN1; SMN2LMNANAAAALDH1A1KDM4E | |
| SCHEMBL22026882 | 0.86 | LMNA (0.45) | SMN1; SMN2LMNANAAAALDH1A1KDM4E | |
| SCHEMBL22027167 | 0.86 | PLK1 (0.45) | SMN1; SMN2LMNANAAAALDH1A1KDM4E | |
| SCHEMBL22027046 | 0.85 | ESR1 (0.35) | SMN1; SMN2LMNAALDH1A1MAPTSLC6A3 | |
| SCHEMBL22027200 | 0.85 | KMT2A (0.45) | SMN1; SMN2LMNANAAAALDH1A1KDM4E | |
| SCHEMBL22026957 | 0.81 | NAAA (0.49) | SMN1; SMN2LMNANAAAALDH1A1MAPK1 | |
| SCHEMBL22026919 | 0.80 | NAAA (0.46) | SMN1; SMN2LMNANAAAALDH1A1KDM4E | |
| SCHEMBL22027158 | 0.79 | ESR1 (0.35) | SMN1; SMN2LMNANAAAALDH1A1SLC6A3 | |
| SCHEMBL22027030 | 0.79 | NAAA (0.44) | SMN1; SMN2LMNANAAAMAPTMAPK1 | |
| SCHEMBL22027033 | 0.76 | ESR1 (0.37) | LMNAALDH1A1MAPTSLC6A3P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002309-A1 | SSAO INHIBITORS AND USES THEREOF | METACRINE, INC. | 2022-01-06 | — | — | US | disclosed |
| CN-113226296-A | SSAO inhibitors and uses thereof | 梅塔科林公司 | 2021-08-06 | — | — | CN | disclosed |
| US-20200181104-A1 | SSAO INHIBITORS AND USES THEREOF | METACRINE, INC. | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002309-A1 | SSAO INHIBITORS AND USES THEREOF | AOX1, AOC2, MAOA | SMN1; SMN2 1556/4885LMNA 1461/4885NAAA 720/4885 |
| US-20200181104-A1 | SSAO INHIBITORS AND USES THEREOF | AOX1, AOC2, MAOA | SMN1; SMN2 1556/4885LMNA 1461/4885NAAA 720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.