Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22004342 | 0.81 | TP53 (0.41) | ALDH1A1KMT2AMEN1TSHRPSEN1 | |
| SCHEMBL23714903 | 0.80 | CA2 (0.36) | ALDH1A1KMT2AMEN1PYCR1HPGD | |
| SCHEMBL19133209 | 0.79 | APLNR (0.34) | KMT2AMEN1PYCR1CYP1A2MAPT | |
| SCHEMBL27891575 | 0.79 | KMT2A (0.33) | ALDH1A1KMT2AMEN1PYCR1LMNA | |
| SCHEMBL30395710 | 0.79 | RORC (0.45) | KMT2AMEN1TSHRHPGDCYP1A2 | |
| SCHEMBL631530 | 0.79 | RORC (0.45) | KMT2AMEN1TSHRHPGDCYP1A2 | |
| SCHEMBL10407969 | 0.79 | GAA (0.36) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL24313236 | 0.77 | HPGD (0.36) | ALDH1A1KMT2AMEN1TSHRHPGD | |
| SCHEMBL3238012 | 0.77 | GABRA1 (0.46) | ALDH1A1KMT2AMEN1TSHRPYCR1 | |
| SCHEMBL30609618 | 0.77 | GABRA1 (0.46) | ALDH1A1KMT2AMEN1TSHRPYCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200165272-A1 | BORATE COMPOUND, AND SYNTHESIS METHOD THEREFOR AND USES THEREOF | CHENGDU ORIGIN BIOTECHNOLOGY LIMITED COMPANY (CN) | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200165272-A1 | BORATE COMPOUND, AND SYNTHESIS METHOD THEREFOR AND USES THEREOF | PSMB11, PSMC5, SEM1 | ALDH1A1 3956/4885KMT2A 1731/4885MEN1 516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.