SCHEMBL22029350

SCHEMBL22029350

COC(=O)CCNC(=O)c1cnc(NS(=O)(=O)c2ccc(Oc3ccc(CCCCCCCCCCCCCC(=O)OC(C)(C)C)cc3)cc2)nc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.41
▸ TBXA2R P21731 1/20 0.39
▸ TBXAS1 P24557 1/20 0.39
▸ CCR9 P51686 1/20 0.38
▸ MEN1 O00255 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ PTPN1 P18031 1/20 0.36
▸ PTPN11 Q06124 1/20 0.36
▸ PTPN22 Q9Y2R2 1/20 0.36
▸ PLAAT3 P53816 1/20 0.36
▸ PLAAT5 Q96KN8 1/20 0.36
▸ PLAAT2 Q9NWW9 1/20 0.36
▸ PLAAT4 Q9UL19 1/20 0.36
▸ ALDH1A1 P00352 2/20 0.35
▸ CASP6 P55212 1/20 0.35
▸ HDAC3 O15379 1/20 0.35
▸ HDAC4 P56524 1/20 0.35
▸ HDAC1 Q13547 1/20 0.35
▸ HDAC7 Q8WUI4 1/20 0.35
▸ HDAC2 Q92769 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22029368 0.90 TDP1 (0.45) TDP1TBXA2RTBXAS1CCR9MEN1
SCHEMBL24257938 0.88 TDP1 (0.44) TDP1CCR9MEN1KMT2A
SCHEMBL22105974 0.87 TDP1 (0.37) TDP1TBXA2RTBXAS1CCR9MEN1
SCHEMBL31682097 0.82 TBXA2R (0.43) TDP1TBXA2RTBXAS1CCR9ALDH1A1
SCHEMBL31682020 0.82 TBXA2R (0.43) TDP1TBXA2RTBXAS1CCR9ALDH1A1
SCHEMBL31681966 0.82 TBXA2R (0.43) TDP1TBXA2RTBXAS1CCR9ALDH1A1
SCHEMBL22029351 0.81 TDP1 (0.41) TDP1TBXA2RTBXAS1MEN1KMT2A
SCHEMBL31682088 0.80 MCL1 (0.40) TDP1TBXA2RTBXAS1HDAC3HDAC4
SCHEMBL31682034 0.80 TDP1 (0.46) TDP1TBXA2RTBXAS1MEN1KMT2A
SCHEMBL22029360 0.80 ALDH1A1 (0.37) TDP1TBXA2RTBXAS1CCR9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3893934-B1 INSULIN CONJUGATES SANOFI SA (FR) 2025-09-10 — — EP disclosed
EP-3894391-A1 PEPTIDE BINDER SANOFI (FR) 2021-10-20 — — EP disclosed
WO-2020120479-A1 PEPTIDE BINDER SANOFI (FR) 2020-06-18 — — WO disclosed
US-20200181223-A1 INSULIN CONJUGATES SANOFI (FR) 2020-06-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200181223-A1 INSULIN CONJUGATES IAPP, INSR, IGF1R TDP1 4783/4885TBXA2R 2334/4885TBXAS1 1562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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