Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | CCR9 | P51686 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.38 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.38 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24257938 | 0.91 | TDP1 (0.44) | TDP1CCR9MEN1KMT2AAKT1 | |
| SCHEMBL22029350 | 0.90 | TDP1 (0.41) | TDP1CCR9TBXAS1TBXA2RMEN1 | |
| SCHEMBL22080450 | 0.86 | ALDH1A1 (0.39) | TDP1POLBNPC1RAB9AMEN1 | |
| SCHEMBL22080331 | 0.83 | TDP1 (0.38) | TDP1POLBTBXAS1TBXA2RNPC1 | |
| SCHEMBL24257979 | 0.82 | MEN1 (0.37) | TDP1POLBNPC1RAB9AMEN1 | |
| SCHEMBL22105974 | 0.82 | TDP1 (0.37) | TDP1CCR9TBXAS1TBXA2RMEN1 | |
| SCHEMBL24257968 | 0.81 | TDP1 (0.42) | TDP1TBXAS1HDAC6EGLN2EGLN1 | |
| SCHEMBL24257966 | 0.81 | TDP1 (0.50) | TDP1NPC1RAB9AHDAC6ALDH1A1 | |
| SCHEMBL24257988 | 0.78 | NPC1 (0.40) | TDP1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL22029401 | 0.78 | NPC1 (0.40) | TDP1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2022-02-17 | — | — | US | disclosed |
| EP-3893934-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2021-10-20 | — | — | EP | disclosed |
| EP-3894391-A1 | PEPTIDE BINDER | SANOFI (FR) | 2021-10-20 | — | — | EP | disclosed |
| WO-2020120479-A1 | PEPTIDE BINDER | SANOFI (FR) | 2020-06-18 | — | — | WO | disclosed |
| WO-2020120463-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2020-06-18 | — | — | WO | disclosed |
| US-20200181223-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200181223-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | TDP1 4783/4885CCR9 3641/4885POLB 4107/4885 |
| US-20220048968-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | TDP1 4783/4885CCR9 3641/4885POLB 4107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.