Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 9/20 | 0.42 |
| ▸ | IRS1 | P35568 | 3/20 | 0.42 |
| ▸ | GAB1 | Q13480 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CCR9 | P51686 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22029368 | 0.91 | TDP1 (0.45) | TDP1AKT1IRS1GAB1CCR9 | |
| SCHEMBL22029350 | 0.88 | TDP1 (0.41) | TDP1CCR9MEN1KMT2A | |
| SCHEMBL22079909 | 0.83 | AKT1 (0.48) | TDP1AKT1IRS1GAB1KDM4E | |
| SCHEMBL22105974 | 0.83 | TDP1 (0.37) | TDP1CCR9MEN1KMT2A | |
| SCHEMBL22079911 | 0.82 | ALDH1A1 (0.38) | TDP1AKT1IRS1GAB1SMN1; SMN2 | |
| SCHEMBL24257935 | 0.81 | SMN1; SMN2 (0.40) | TDP1AKT1IRS1GAB1KDM4E | |
| SCHEMBL22080450 | 0.78 | ALDH1A1 (0.39) | TDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22080431 | 0.77 | KDM4E (0.54) | AKT1IRS1GAB1KDM4ELMNA | |
| SCHEMBL24257837 | 0.76 | TP53 (0.48) | TDP1AKT1IRS1GAB1KDM4E | |
| SCHEMBL24257940 | 0.76 | AKT1 (0.42) | TDP1AKT1IRS1GAB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | TDP1 4783/4885AKT1 1118/4885IRS1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.