SCHEMBL8917508

SCHEMBL8917508

Nc1c(-c2ccccc2)ccc(C(F)(F)F)c1N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 2/20 0.40
ALDH1A1 P00352 1/20 0.40
ACHE P22303 2/20 0.39
MAPT P10636 1/20 0.39
KIF11 P52732 2/20 0.39
S1PR1 P21453 2/20 0.37
S1PR3 Q99500 2/20 0.37
DPP4 P27487 1/20 0.37
BACE1 P56817 1/20 0.37
HSD11B1 P28845 1/20 0.37
ADORA3 P0DMS8 1/20 0.36
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
KDM4E B2RXH2 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MET P08581 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28952310 0.90 BACE1 (0.41) ALDH1A1MAPTS1PR1BACE1HPGD
Sulfuric Acid SCHEMBL29237768 0.90 MAPT (0.37) GLAPOLBGAATSHRHSD17B10
Sulfuric Acid SCHEMBL29237825 0.87 RORC (0.35) GLAPOLBGAATSHRALDH1A1
SCHEMBL27920522 0.85 GLA (0.38) GLAPOLBGAATSHRHSD17B10
SCHEMBL3790614 0.84 ALDH1A1 (0.45) POLBHSD17B10ALDH1A1ACHEMAPT
SCHEMBL27806632 0.83 HSD11B1 (0.41) GLAPOLBGAATSHRHSD17B10
SCHEMBL29634287 0.82 KIF11 (0.50) GLAPOLBGAATSHRKIF11
SCHEMBL4107003 0.80 ALDH1A1 (0.57) GLATSHRHSD17B10ALDH1A1MAPT
SCHEMBL7450010 0.78 POLB (0.46) GLAPOLBGAATSHRHSD17B10
SCHEMBL2202989 0.76 ACHE (0.40) GLAPOLBGAATSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 791 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118543213-A Device for enriching rare gas by multi-physical field enhanced membrane separation 昆明理工大学 2024-08-27 CN claimed
CN-118344591-A Preparation method of thermosetting polyimide material using water as solvent 江苏海洋大学 2024-07-16 CN claimed
CN-115723393-B Support body and application thereof 杭州福斯特应用材料股份有限公司 2024-07-16 CN claimed
CN-118344590-A Polyamic acid containing trifluoro and amide bonds, and preparation method and application thereof 株洲时代新材料科技股份有限公司 2024-07-16 CN claimed
CN-118290794-A Coating type modified polyimide film with carrier film and preparation method thereof 昆山雅森电子材料科技有限公司 2024-07-05 CN claimed
CN-118290733-A Polyimide with high fluorine content, gas separation membrane, and preparation method and application thereof 大连理工大学 2024-07-05 CN claimed
CN-118271610-A Polyamic acid slurry for optical fiber and preparation method and application thereof 宁波博雅聚力新材料科技有限公司 2024-07-02 CN claimed
CN-118281310-A PVDF-HFP/COF-F/PMMA composite solid electrolyte membrane and preparation method and application thereof 华南师范大学 2024-07-02 CN claimed
CN-118271609-A Polyamic acid slurry and preparation method and application thereof 宁波博雅聚力新材料科技有限公司 2024-07-02 CN claimed
CN-115000364-B Polyimide coated modified lithium ion battery anode active material, preparation method and application 北京化工大学常州先进材料研究院 2024-07-02 CN claimed
CN-111205642-A Transparent polyimide film 达迈科技股份有限公司 2020-05-29 CN claimed
CN-111205457-A Method for producing polyimide film 达迈科技股份有限公司 2020-05-29 CN claimed
CN-111205490-A Method for producing polyimide film 达迈科技股份有限公司 2020-05-29 CN claimed
CN-111138695-A Polyimide film and preparation method thereof 深圳先进电子材料国际创新研究院 2020-05-12 CN claimed
CN-111093323-A Circuit substrate and preparation method thereof 住井工业(湖南)有限公司 2020-05-01 CN claimed
CN-108735349-B Silver nanowire transparent conductive film containing ionic liquid and preparation method thereof 东南大学 2020-03-31 CN claimed
CN-110938220-A Method for preparing transparent polyimide film 达迈科技股份有限公司 2020-03-31 CN claimed
CN-110922754-A Preparation method and application of polyimide film 南京湘珀新材料科技有限公司 2020-03-27 CN claimed
CN-110790929-A Colorless transparent high-modulus polyimide film and preparation method thereof 上海金門量子科技有限公司 2020-02-14 CN claimed
US-5686525-A THIXOTROPIC SCREEN PRINTING INK COMPRISING A HEAT TREATED POLYAMIC ACID SOLUTION OBTAINED BY REACTION OF AROMATIC TETRACARBOXYLIC ACID, DIAMINE AND A MALEIMIDE; RELIEF IMAGES CENTRAL GLASS COMPANY, LTD. (JP) 1997-11-11 US claimed