SCHEMBL27920522

SCHEMBL27920522

Nc1c(-c2ccccc2)ccc(C(F)(F)F)c1C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 2/20 0.38
ALDH1A1 P00352 1/20 0.38
ACHE P22303 2/20 0.37
MAPT P10636 1/20 0.37
KIF11 P52732 2/20 0.36
S1PR1 P21453 2/20 0.36
S1PR3 Q99500 2/20 0.36
DPP4 P27487 1/20 0.35
BACE1 P56817 1/20 0.35
HSD11B1 P28845 2/20 0.35
ADORA3 P0DMS8 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
KDM4E B2RXH2 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MET P08581 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8917508 0.85 GLA (0.41) GLAPOLBGAATSHRHSD17B10
SCHEMBL7211572 0.83 ALDH1A1 (0.43) POLBGAATSHRHSD17B10ALDH1A1
SCHEMBL29269098 0.81 KIF11 (0.40) GLAPOLBGAATSHRHSD17B10
SCHEMBL27083623 0.80 ALDH1A1 (0.46) GLAPOLBGAATSHRHSD17B10
SCHEMBL2849367 0.80 ACHE (0.40) GLAPOLBGAATSHRHSD17B10
SCHEMBL2202989 0.80 ACHE (0.40) GLAPOLBGAATSHRHSD17B10
SCHEMBL29914889 0.79 KIF11 (0.47) ALDH1A1KIF11S1PR1S1PR3HSD11B1
SCHEMBL3790614 0.77 ALDH1A1 (0.45) POLBHSD17B10ALDH1A1ACHEMAPT
SCHEMBL29266608 0.76 ACHE (0.40) GLAPOLBGAATSHRHSD17B10
SCHEMBL27806632 0.76 HSD11B1 (0.41) GLAPOLBGAATSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105408948-A Substrate for organic electronic device LG CHEMICAL LTD 2016-03-16 CN disclosed
CN-105408949-A Method for manufacturing substrate for organic electronic device LG CHEMICAL LTD 2016-03-16 CN disclosed
CN-102692661-B The manufacture method of colored filter, colored filter and liquid crystal display cells JSR CORP. (JP) 2016-01-06 CN disclosed
CN-102955188-B The manufacture method of colored filter, liquid crystal display cells and colored filter JSR CO., LTD. (JP) 2015-12-09 CN disclosed
CN-105103042-A Array substrate, liquid crystal display element, and radiation-sensitive resin composition JSR CORP 2015-11-25 CN disclosed
CN-103543607-A Organic EL element, radiation-sensitive resin composition, and cured film JSR CORP 2014-01-29 CN disclosed
CN-102089711-B Positive photosensitive resin composition and polyhydroxyamide resin NISSAN CHEMICAL IND LTD 2013-05-22 CN disclosed