Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKLR | P30613 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | YAP1 | P46937 | 1/20 | 0.47 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.47 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22032771 | 0.82 | TGM2 (0.60) | ALDH1A1SMN1; SMN2LMNAPKM | |
| SCHEMBL19858517 | 0.81 | PKM (0.76) | ALDH1A1SMN1; SMN2LMNAPKMNPC1 | |
| SCHEMBL6886969 | 0.81 | USP2 (0.65) | ALDH1A1SMN1; SMN2LMNAPKMNPC1 | |
| SCHEMBL22032773 | 0.80 | KMT2A (0.59) | ALDH1A1SMN1; SMN2LMNAPKMNPC1 | |
| SCHEMBL17100765 | 0.78 | MAPT (0.58) | ALDH1A1SMN1; SMN2LMNAPKMNPC1 | |
| SCHEMBL8218729 | 0.77 | LMNA (0.53) | ALDH1A1SMN1; SMN2LMNAPKMNPC1 | |
| SCHEMBL6744239 | 0.77 | ALDH1A1 (0.71) | ALDH1A1LMNAPKMNPC1KMT2A | |
| SCHEMBL2835516 | 0.77 | KMT2A (0.56) | ALDH1A1SMN1; SMN2LMNAPKMMEN1 | |
| SCHEMBL2959791 | 0.77 | PKM (0.51) | ALDH1A1SMN1; SMN2LMNAPKMNPC1 | |
| SCHEMBL7373758 | 0.77 | L3MBTL1 (0.48) | ALDH1A1LMNAPKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3890715-A1 | THERAPEUTICS TARGETING MUTANT ADENOMATOUS POLYPOSIS COLI (APC) FOR THE TREATMENT OF CANCER | The Board Of Regents Of The University Of Texas System (US) | 2021-10-13 | — | — | EP | disclosed |
| WO-2020117972-A1 | THERAPEUTICS TARGETING MUTANT ADENOMATOUS POLYPOSIS COLI (APC) FOR THE TREATMENT OF CANCER | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-06-11 | — | — | WO | disclosed |