Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2202386 | 0.86 | CHRM2 (0.50) | CXCR4MAOAHRH4HRH3CHRM2 | |
| SCHEMBL2202962 | 0.85 | SCN8A (0.40) | CXCR4CA2HRH4HRH3CHRM2 | |
| SCHEMBL12509867 | 0.85 | MAOA (0.43) | CXCR4MAOAHRH4HRH3CHRM2 | |
| SCHEMBL2203351 | 0.83 | ALDH1A1 (0.43) | CXCR4CA2CHRM2CA1SMN1; SMN2 | |
| SCHEMBL2203380 | 0.82 | CXCR4 (0.39) | CXCR4HRH4HRH3CHRM2CA1 | |
| SCHEMBL2204056 | 0.79 | CXCR4 (0.54) | CXCR4HRH4HRH3CHRM2SMN1; SMN2 | |
| SCHEMBL12510185 | 0.78 | HRH4 (0.47) | CXCR4MAOAHRH4HRH3CHRM2 | |
| SCHEMBL4947145 | 0.78 | CA2 (0.42) | CA2CHRM2CA1SMN1; SMN2DRD2 | |
| SCHEMBL2201877 | 0.78 | SMN1; SMN2 (0.45) | CXCR4HRH4HRH3CHRM2SMN1; SMN2 | |
| SCHEMBL12426446 | 0.77 | CXCR4 (0.43) | CXCR4HRH4HRH3CHRM2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722719-B2 | Amine compound and use for same | KUREHA CORPORATION (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20130245280-A1 | AMINE COMPOUND AND USE FOR SAME | KUREHA CORPORATION (JP) | 2013-09-19 | — | — | US | disclosed |
| EP-2626349-A1 | AMINE COMPOUND AND USE FOR SAME | Kureha Corporation (JP) | 2013-08-14 | — | — | EP | disclosed |
| US-7977512-B2 | Amine derivative, and production method and use thereof | KUREHA CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7977512-B2 | Amine derivative, and production method and use thereof | KUREHA CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7977512-B2 | Amine derivative, and production method and use thereof | KUREHA CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |
| US-20080293951-A1 | Amin Derivative, and Production Method and Use Thereof | KUREHA CORPORATION | 2008-11-27 | — | — | US | disclosed |
| US-20080293951-A1 | Amin Derivative, and Production Method and Use Thereof | KUREHA CORPORATION | 2008-11-27 | — | — | US | disclosed |
| US-20080293951-A1 | Amin Derivative, and Production Method and Use Thereof | KUREHA CORPORATION | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130245280-A1 | AMINE COMPOUND AND USE FOR SAME | SAT1, ALDH7A1, HNMT | CXCR4 4194/4885MAOA 83/4885CA2 1210/4885 |
| US-20080293951-A1 | Amin Derivative, and Production Method and Use Thereof | BCAT2, BCAT1, MRPL9 | CXCR4 2546/4885MAOA 632/4885CA2 1761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.