SCHEMBL22041005

SCHEMBL22041005

CC(C)N1C(=O)c2ccc(F)cc2C1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARK7 Q99497 2/20 0.41
DDB1 Q16531 1/20 0.41
CRBN Q96SW2 1/20 0.41
AR P10275 5/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
ALDH1A1 P00352 2/20 0.38
ALOX15 P16050 1/20 0.38
TRPA1 O75762 1/20 0.38
ACHE P22303 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MAPT P10636 2/20 0.36
LMNA P02545 1/20 0.35
MEN1 O00255 1/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2665475 0.78 MAOA (0.50) CA1CA2CA9ALDH1A1LMNA
SCHEMBL8417452 0.78 ALDH1A1 (0.55) PARK7DDB1CRBNARCA1
SCHEMBL12540874 0.77 TDP1 (0.43) ALDH1A1TDP1MAPTLMNAMEN1
SCHEMBL21976969 0.77 ANPEP (0.55) TDP1MEN1KMT2A
SCHEMBL2741635 0.77 LMNA (0.48) CA1CA2CA9ALDH1A1ALOX15
SCHEMBL24303348 0.77 S100A4 (0.47) MAPTMEN1KMT2A
SCHEMBL1950000 0.77 ANPEP (0.55) DDB1CRBNALDH1A1ALOX15TDP1
SCHEMBL1686814 0.77 ESR1 (0.50) DDB1CRBNCA1CA2CA7
SCHEMBL17254677 0.77 PARK7 (0.45) PARK7CA1CA2CA7CA9
SCHEMBL30863794 0.77 ALDH1A1 (0.41) ARCA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200172527-A1 BENZOXAZINONE DERIVATIVES USEFUL AS HERBICIDES REDAG CROP PROT LTD (GB) 2020-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200172527-A1 BENZOXAZINONE DERIVATIVES USEFUL AS HERBICIDES CBR3, CBR1, CYP4X1 PARK7 3489/4885DDB1 2201/4885CRBN 2720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.